CAS 1424635-83-5

1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, N-[3-(phenylmethyl)-2(3H)-thiazolylidene]-

Description:

1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, N-[3-(phenylmethyl)-2(3H)-thiazolylidene]- is a complex organic compound characterized by its unique structural features, which include a pyrrolo[2,3-b]pyridine core and a thiazole moiety. This compound typically exhibits properties associated with heterocyclic compounds, such as potential biological activity and solubility in organic solvents. The presence of the thiazole group may contribute to its reactivity and interaction with biological targets, making it of interest in medicinal chemistry. The compound's molecular structure suggests it may participate in hydrogen bonding and π-π stacking interactions, which are important for its potential applications in drug design. Additionally, the phenylmethyl substituent can enhance lipophilicity, influencing its pharmacokinetic properties. Overall, this compound's characteristics make it a candidate for further investigation in the fields of pharmaceuticals and organic synthesis, particularly in the development of new therapeutic agents.

Formula: C₁₈H₁₄N₄OS

InChI: InChI=1S/C18H14N4OS/c23-17(15-11-20-16-14(15)7-4-8-19-16)21-18-22(9-10-24-18)12-13-5-2-1-3-6-13/h1-11H,12H2,(H,19,20)

InChI key: VTXBMVZVPUSAJF-UHFFFAOYSA-N

SMILES: C1=CC=C(C=C1)CN2C=CSC2=NC(=O)C3=CNC4=C3C=CC=N4

Synonyms:

• TRULI
• 1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, N-[3-(phenylmethyl)-2(3H)-thiazolylidene]-
• Lats-IN-1(TRULI )
• Lats-IN-1

N-(3-Benzylthiazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide

CAS: 1424635-83-5

N-(3-Benzylthiazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide

Formula: C₁₈H₁₄N₄OS

Purity: 98%

Molecular weight: 334.4

Ref: 54-OR1023286

TRULI

CAS: 1424635-83-5

Formula: C₁₈H₁₄N₄OS

Purity: 98%

Molecular weight: 334.3950

Ref: IN-DA01X5O6

Lats-IN-1

CAS: 1424635-83-5

Lats-IN-1

Formula: C₁₈H₁₄N₄OS

Purity: ≥95%

Molecular weight: 334.39

Ref: 54-BUP12434

TRULI

CAS: 1424635-83-5

N-(3-Benzylthiazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide

Formula: C₁₈H₁₄N₄OS

Purity: 98%

Molecular weight: 334.4

Ref: IN-DG01239115

Lats-IN-1

CAS: 1424635-83-5

Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.

Formula: C₁₈H₁₄N₄OS

Purity: 97.54% - 99.79%

Color and Shape: White Solid

Molecular weight: 334.39

Ref: TM-T9053

Lats-in-1

CAS: 1424635-83-5

Lats-in-1 is a potent inhibitor of the protein tyrosine phosphatase. This inhibitory effect is not due to its ability to bind to the catalytic site of the enzyme, but rather is due to its ability to bind to other regions of the protein that are not involved in catalysis. Lats-in-1 has been shown to bind selectively and specifically with high affinity and specificity to both recombinant and native proteins. Lats-in-1 has been used as a research tool for studying protein interactions, ligand binding and receptor activation.

Formula: C₁₈H₁₄N₄OS

Purity: Min. 95%

Molecular weight: 334.4 g/mol

Ref: 3D-ZGC63583