CAS 1425381-60-7: gusacitinib

Description:Gusacitinib is a small molecule inhibitor primarily targeting Janus kinase (JAK) enzymes, specifically JAK1 and JAK2, which play crucial roles in the signaling pathways of various cytokines and growth factors. This compound is being investigated for its potential therapeutic applications in autoimmune diseases and certain inflammatory conditions. Its mechanism of action involves the modulation of immune responses by inhibiting the JAK-STAT signaling pathway, thereby reducing inflammation and altering immune cell function. Gusacitinib is characterized by its selective inhibition, which aims to minimize side effects associated with broader immunosuppressive therapies. The substance is typically administered orally and has undergone various phases of clinical trials to evaluate its efficacy and safety profile. As with many investigational drugs, the pharmacokinetics, metabolism, and potential drug interactions are critical areas of study to ensure optimal therapeutic outcomes. Overall, gusacitinib represents a promising avenue in the development of targeted therapies for complex immune-mediated disorders.

Synonyms:
GUSACITINIB
1-[5,6-Dihydro-4-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5-oxopyrimido[4,5-d]pyridazin-2-yl]-4-piperidineacetonitrile
2-(1-(4-((4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5-oxo-5,6-dihydropyrimido[4,5-d]pyridazin-2-yl)piperidin-4-yl)acetonitrile
4-Piperidineacetonitrile, 1-[5,6-dihydro-4-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5-oxopyrimido[4,5-d]pyridazin-2-yl]-

Found 4 products.

Product data	Purity	Price range	Estimated delivery
Gusacitinib REF: TM-T14331CAS: 1425381-60-7	99.94%	42.00 €~750.00 €	Mon 14 Apr 25
Gusacitinib REF: IN-DA01FPMDCAS: 1425381-60-7	98%	118.00 €~563.00 €	Mon 14 Apr 25
Gusacitinib REF: 54-BUP08977CAS: 1425381-60-7	99.93%	291.00 €~1,099.00 €	Tue 15 Apr 25
Gusacitinib REF: 3D-AHC38160CAS: 1425381-60-7	Min. 95%	To inquire	Tue 27 May 25