CymitQuimica logo

CAS 142561-96-4

:

Zaragozic acid A

Description:
Zaragozic acid A is a natural product belonging to the class of triterpenoids, specifically a type of lanostane. It is primarily known for its role as a potent inhibitor of squalene synthase, an enzyme critical in the biosynthesis of sterols, including cholesterol. This inhibition makes zaragozic acid A of interest in pharmaceutical research, particularly for its potential applications in treating hypercholesterolemia and other related conditions. The compound is characterized by its complex polycyclic structure, which contributes to its biological activity. Zaragozic acid A is typically isolated from fungal sources, particularly certain species of the genus *Penicillium*. Its chemical properties include solubility in organic solvents and stability under specific conditions, although it may be sensitive to light and heat. As a research compound, it has been studied for its effects on lipid metabolism and its potential therapeutic benefits, although further studies are necessary to fully understand its mechanisms and applications in medicine.
Formula:C35H46O14
InChI:InChI=1S/C35H46O14/c1-7-19(2)17-20(3)13-14-25(37)47-28-27(38)33(48-29(30(39)40)34(45,31(41)42)35(28,49-33)32(43)44)16-15-21(4)26(46-23(6)36)22(5)18-24-11-9-8-10-12-24/h8-14,19-20,22,26-29,38,45H,4,7,15-18H2,1-3,5-6H3,(H,39,40)(H,41,42)(H,43,44)/b14-13+/t19-,20+,22+,26+,27+,28+,29+,33-,34+,35-/m0/s1
InChI key:InChIKey=DFKDOZMCHOGOBR-NCSQYGPNSA-N
SMILES:C(O)(=O)[C@]12[C@H](OC(/C=C/[C@H](C[C@H](CC)C)C)=O)[C@@H](O)[C@](CCC([C@H]([C@@H](CC3=CC=CC=C3)C)OC(C)=O)=C)(O1)O[C@H](C(O)=O)[C@]2(C(O)=O)O
Synonyms:
  • (1S,3S,4S,5R,6R,7R)-1-[(4S,5R)-4-(acetyloxy)-5-methyl-3-methylidene-6-phenylhexyl]-6-{[(2E,4S,6S)-4,6-dimethyloct-2-enoyl]oxy}-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid (non-preferred name)
  • (1S,3S,4S,5R,6R,7R)-1-[(4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenylhexyl]-6-{[(2E,4S,6S)-4,6-dimethyloct-2-enoyl]oxy}-4,7-dihydroxy-2,8-dioxabicyclo[3.2.1]octane-3,4,5-tricarboxylic acid (non-preferred name)
  • 142561-96-4
  • 2,8-Dioxabicyclo[3.2.1]octane, <span class="text-smallcaps">L</smallcap>-erythro-<smallcap>L</smallcap>-glycero-<smallcap>D</span>-altro-7-trideculo-7,4-furanosonic acid deriv.
  • <span class="text-smallcaps">L</smallcap>-erythro-<smallcap>L</smallcap>-glycero-<smallcap>D</span>-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-(4,6-dimethyl-2-octenoate), [5(2E,4S,6S),7S]-
  • <span class="text-smallcaps">L</smallcap>-erythro-<smallcap>L</smallcap>-glycero-<smallcap>D</span>-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-
  • Gr 105155X
  • L 694599
  • Squalestatin
  • Squalestatin 1
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.