CAS 1425793-87-8

Clomipramine HCl EP Impurity G

Description:

Clomipramine HCl EP Impurity G, with the CAS number 1425793-87-8, is a chemical compound that is recognized as an impurity associated with the antidepressant clomipramine, which is primarily used to treat obsessive-compulsive disorder and depression. As an impurity, it may arise during the synthesis or degradation of clomipramine and is typically characterized by its specific molecular structure and properties. While detailed information on this particular impurity may be limited, impurities in pharmaceuticals are often assessed for their potential impact on safety and efficacy. Characteristics of such impurities can include their solubility, stability, and reactivity, which are crucial for quality control in pharmaceutical manufacturing. Regulatory guidelines often require the identification and quantification of impurities to ensure that they remain within acceptable limits to safeguard patient health. Analytical techniques such as chromatography and mass spectrometry are commonly employed to characterize and quantify impurities like Clomipramine HCl EP Impurity G in pharmaceutical formulations.

Formula: C₁₇H₁₆ClN

Synonyms:

• 3-Chloro-5-(prop-2-en-1-yl)-10,11-dihydro-5H-dibenzo[b,f]azepine
• Clomipramine HCl EP Impurity G
• 3-Chloro-5-(prop-2-enyl)-10,11-dihydro-5H-dibenzo[b,f]azepine
• Clomipramine EP Impurity G
• N-Allyl-3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepine
• Clomipramine Hydrochloride EP Impurity G
• Clomipramine Impurity 7（Clomipramine EP Impurity G）

Clomipramine HCl EP Impurity G

CAS: 1425793-87-8

Formula: C₁₇H₁₆ClN

Color and Shape: Colorless Oil

Molecular weight: 269.77

Ref: 4Z-C-195006

3-Chloro-5-(prop-2-enyl)-10,11-dihydro-5H-dibenzo[b,f]azepine

Controlled Product

CAS: 1425793-87-8

Formula: C₁₇H₁₆ClN

Color and Shape: Neat

Molecular weight: 269.77

Ref: 86-MM0545.07

N-Allyl-3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepine

Controlled Product

CAS: 1425793-87-8

Applications N-Allyl-3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepine is a metabolite of Clomipramine (C587050, HCl); a serotonin reuptake inhibitor. Clomipramine is also an antidepressant and antiobsessional agent.
References Peters, M.D., et al.: Clin. Pharm., 9, 165 (1990); Adamczyk, M., et al.: Ther. Drug Monit., 17, 371 (1995); Poolsup, N., et al.: J. Clin. Pharm. Ther., 25, 197 (2000); Bose, D., et al.: J. Pharmacol. Toxicol. Methods, 52, 323 (2005)

Formula: C₁₇H₁₆ClN

Color and Shape: Light Yellow

Molecular weight: 269.77

Ref: TR-A549725

Clomipramine Hydrochloride EP Impurity G

CAS: 1425793-87-8

Formula: C₁₇H₁₆ClN

Molecular weight: 269.77

Ref: ST-EA-CP-C30010