CAS 14259-45-1

Asperuloside

Description:

Asperuloside is a naturally occurring glycoside, primarily derived from various plant species, including those in the Rubiaceae family. It is characterized by its chemical structure, which consists of a glucose moiety linked to an aglycone, typically a phenolic compound. Asperuloside is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and antimicrobial activities. The substance is often studied for its role in traditional medicine and its potential therapeutic applications. In terms of physical properties, asperuloside is generally soluble in polar solvents, reflecting its glycosidic nature. Its stability can be influenced by factors such as pH and temperature, which are important considerations in both natural and synthetic contexts. Additionally, research into asperuloside has highlighted its significance in phytochemistry and its potential as a bioactive compound in various health-related applications. Overall, asperuloside represents an interesting subject of study within the field of natural products and medicinal chemistry.

Formula: C₁₈H₂₂O₁₁

InChI: InChI=1S/C18H22O11/c1-6(20)25-4-7-2-9-12-8(16(24)27-9)5-26-17(11(7)12)29-18-15(23)14(22)13(21)10(3-19)28-18/h2,5,9-15,17-19,21-23H,3-4H2,1H3/t9-,10+,11+,12-,13+,14-,15+,17-,18-/m0/s1

InChI key: InChIKey=IBIPGYWNOBGEMH-DILZHRMZSA-N

SMILES: O([C@H]1[C@]2([C@@]3([C@](C=C2COC(C)=O)(OC(=O)C3=CO1)[H])[H])[H])[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Synonyms:

• (2aS,4aS,5S,7bS)-4-[(Acetyloxy)methyl]-5-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-1H-2,6-dioxacyclopent[cd]inden-1-one
• (2aS-(2aalpha,4aalpha,5alpha,7balpha))-5-(beta-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-1-oxo-1H-2,6-dioxacyclopent(cd)inden-4-ylmethyl acetate
• 1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)-
• 1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, [2aS-(2aα,4aα,5α,7bα)]-
• 1H-2,6-dioxacyclopent(cd)inden-1-one, 4-((acetyloxy)methyl)-5-(beta-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS-(2aalpha,5alpha,7balpha))-
• Asperuloside
• Cyclopenta[c]pyran-4-carboxylic acid, 1α-(β-<span class="text-smallcaps">D</span>-glucosyloxy)-1,4aα,5,7aα-tetrahydro-5β-hydroxy-7-(hydroxymethyl)-, γ-lactone, 7-acetate
• Nsc 31760
• [(2aS,4aS,5S,7bS)-5-(beta-D-glucopyranosyloxy)-1-oxo-2a,4a,5,7b-tetrahydro-1H-2,6-dioxacyclopenta[cd]inden-4-yl]methyl acetate
• [5-(hexopyranosyloxy)-1-oxo-2a,4a,5,7b-tetrahydro-1H-2,6-dioxacyclopenta[cd]inden-4-yl]methyl acetate
• Cyclopenta[c]pyran-4-carboxylic acid, 1α-(β-D-glucosyloxy)-1,4aα,5,7aα-tetrahydro-5β-hydroxy-7-(hydroxymethyl)-, γ-lactone, 7-acetate
• 1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(β-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, [2aS-(2aα,4aα,5α,7bα)]-
• 1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(β-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)-

Asperuloside

CAS: 14259-45-1

Formula: C₁₈H₂₂O₁₁

Purity: 95%

Color and Shape: Solid

Molecular weight: 414.3607

Ref: IN-DA01DDFH

Asperuloside

CAS: 14259-45-1

Formula: C₁₈H₂₂O₁₁

Molecular weight: 414.36

Ref: 7W-GK4379

Asperuloside

CAS: 14259-45-1

Asperuloside

Purity: ≥98%

Molecular weight: 414.36g/mol

Ref: 54-BUP06513

Asperuloside

CAS: 14259-45-1

Asperuloside exerts its anti-inflammatory effect in correlation with inhibition of a pro-inflammatory mediator through suppressing nuclear factor kappa-B (NF-κB) nuclear translocation and MAPK phosphorylation in a dose-dependent manner. Chronic administration of Asperuloside stimulates anti-obesity and anti-metabolic syndrome activity in HFD-fed rats across several organs, similar to Eucommia leaf extract (ELE) administration.

Formula: C₁₈H₂₂O₁₁

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 414.363

Ref: BP-BP1773

Asperuloside

CAS: 14259-45-1

Asperuloside (Asperulosid) has anti-inflammatory activity.

Formula: C₁₈H₂₂O₁₁

Purity: 98.03% - 99.42%

Color and Shape: Solid

Molecular weight: 414.36

Ref: TM-T3847

Asperuloside

CAS: 14259-45-1

Natural glycoside

Formula: C₁₈H₂₂O₁₁

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 414.36

Ref: 5G-83229

Asperuloside

CAS: 14259-45-1

Anti-obesity

Formula: C₁₈H₂₂O₁₁

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 414.36 g/mol

Ref: 3D-OA35386