CAS 14259-47-3

Didymin

Description:

Didymin, with the CAS number 14259-47-3, is a flavonoid compound primarily found in citrus fruits. It is a glycoside of the flavonoid diosmin, which means it consists of a flavonoid moiety linked to a sugar molecule. Didymin is known for its potential health benefits, including antioxidant properties, which help in neutralizing free radicals in the body. It may also exhibit anti-inflammatory effects and has been studied for its potential role in cardiovascular health. The compound is soluble in organic solvents but has limited solubility in water, which can affect its bioavailability. Didymin is often researched for its pharmacological properties, particularly in the context of dietary supplements and natural health products. Its safety profile is generally considered favorable, although further studies are necessary to fully understand its effects and mechanisms of action in human health. As with many flavonoids, the bioactivity of didymin can be influenced by factors such as dosage, formulation, and individual metabolic differences.

Formula: C₂₈H₃₄O₁₄

InChI: InChI=1S/C28H34O14/c1-11-21(31)23(33)25(35)27(39-11)38-10-19-22(32)24(34)26(36)28(42-19)40-14-7-15(29)20-16(30)9-17(41-18(20)8-14)12-3-5-13(37-2)6-4-12/h3-8,11,17,19,21-29,31-36H,9-10H2,1-2H3/t11-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1

InChI key: InChIKey=RMCRQBAILCLJGU-HIBKWJPLSA-N

SMILES: O=C1C=2C(O[C@@H](C1)C3=CC=C(OC)C=C3)=CC(O[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@H]4O)=CC2O

Synonyms:

• (2S)-7-[[6-O-(6-Deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
• (S)-7-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one
• 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-, (2S)-
• 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-, (S)-
• 4′-Methoxy-5,7-dihydroxyflavanone 7-O-rutinoside
• 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-L-mannopyranosyl)-beta-D-glucopyranoside
• 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxyhexopyranosyl)hexopyranoside
• Citrifoliol-7-O-rutinoside
• Didymine
• Flavanone, 5,7-dihydroxy-4′-methoxy-, 7β-rutinoside
• Isosakuranetin 7-rutinoside
• Isosakuranetin-7-O-rutinoside
• Isosakuranetin-7-beta-rutinoside
• Neoponcirin
• Didymin
• 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-, (S)-
• (2S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one

Didymin

CAS: 14259-47-3

Didymin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₈H₃₄O₁₄

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 594.57

Ref: 11-1166S

(S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one

CAS: 14259-47-3

Formula: C₂₈H₃₄O₁₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 594.5612

Ref: IN-DA0034PP

Didymin

CAS: 14259-47-3

Formula: C₂₈H₃₄O₁₄

Molecular weight: 594.57

Ref: 7W-GY9339

Didymin

CAS: 14259-47-3

Didymin

Purity: ≥98%

Molecular weight: 594.56g/mol

Ref: 54-BUP21061

Didymin

CAS: 14259-47-3

Formula: C₂₈H₃₄O₁₄

Color and Shape: White To Off-White Solid

Molecular weight: 594.57

Ref: 4Z-D-456

Didymin

CAS: 14259-47-3

Didymin is a citrus-derived natural compound that kills p53 wild-type as well as drug-resistant p53-mutant neuroblastoma cells in culture, it induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma. Didymin possesses antioxidant, anti-inflammation and anti-cancer properties.

Formula: C₂₈H₃₄O₁₄

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 594.566

Ref: BP-BP1502

Didymin

CAS: 14259-47-3

Didymin, an antioxidant, may treat neuroblastoma and neurodegeneration by blocking N-Myc and boosting RKIP.

Formula: C₂₈H₃₄O₁₄

Purity: 99.12% - 99.87%

Color and Shape: Faintly Beige Powder

Molecular weight: 594.56

Ref: TM-T3787

Didymin

CAS: 14259-47-3

Natural glycoside

Formula: C₂₈H₃₄O₁₄

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 594.57

Ref: 5G-80584

Neoponcirin

CAS: 14259-47-3

Formula: C₂₈H₃₄O₁₄

Molecular weight: 594.6

Ref: ST-EA-CP-D45008

Neoponcirin

Controlled Product

CAS: 14259-47-3

Applications Neoponcirin is a flavonoid that was shown to exhibit anticancer properties by inducing apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma. References Singhai, J., et al.: Cancer. Prev. Res., 5, 473 (2012); Sdiri, S., et al.: Postharv. Biol. Techol., 65, 13, (2012);

Formula: C₂₈H₃₄O₁₄

Color and Shape: Neat

Molecular weight: 594.56

Ref: TR-N390050

Didymin

CAS: 14259-47-3

Didymin is a flavonoid compound, which is a type of polyphenolic molecule. It occurs naturally in certain citrus fruits and plants, representing a secondary metabolite with bioactive properties. Didymin exhibits antioxidative activity by neutralizing free radicals and reducing oxidative stress, primarily through the modulation of cellular signaling pathways. This mechanism involves the enhancement of endogenous antioxidant defenses and the inhibition of pro-inflammatory mediators.

Formula: C₂₈H₃₄O₁₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 594.56 g/mol

Ref: 3D-FD74159