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CAS 1425938-66-4

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Fmoc-(Dmb)Ala-OH

Description:
Fmoc-(Dmb)Ala-OH, or 9-fluorenylmethoxycarbonyl-(Dmb)alanine, is a protected amino acid commonly used in peptide synthesis. The Fmoc group serves as a protective group for the amino functionality, allowing for selective reactions during the synthesis process. The presence of the Dmb (2,4-dimethylbenzyl) side chain provides additional steric hindrance and can influence the peptide's folding and stability. This compound is typically characterized by its solid-state form, which is stable under standard laboratory conditions, and it is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane. The compound's structure allows for easy removal of the Fmoc group under basic conditions, facilitating the subsequent coupling of other amino acids. Its application in solid-phase peptide synthesis highlights its importance in the production of peptides with specific sequences and functionalities. Overall, Fmoc-(Dmb)Ala-OH is a valuable building block in the field of organic and medicinal chemistry, particularly in the development of peptide-based therapeutics.
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