CAS 1426173-86-5

Silodosin-d4

Description:

Silodosin-d4 is a deuterated form of Silodosin, which is primarily used as a medication for the treatment of benign prostatic hyperplasia (BPH). As a deuterated compound, Silodosin-d4 contains four deuterium atoms, which are isotopes of hydrogen, replacing the regular hydrogen atoms in the molecular structure. This modification can enhance the stability and metabolic tracking of the compound in pharmacokinetic studies. Silodosin itself is an alpha-1 adrenergic receptor antagonist, which works by relaxing the muscles in the prostate and bladder neck, thereby improving urine flow. The deuterated version is often utilized in research settings to study drug metabolism and pharmacodynamics without interference from the natural isotopes of hydrogen. In terms of physical properties, Silodosin-d4 would exhibit similar characteristics to its non-deuterated counterpart, including solubility and reactivity, but with altered isotopic effects that may influence its behavior in biological systems. Overall, Silodosin-d4 serves as a valuable tool in pharmaceutical research and development.

Formula: C₂₅H₃₂F₃N₃O₄

Synonyms:

• [2H4]-Silodosin (Chiral)
• Silodosin-d4 (Chiral)

Silodosin-d4

CAS: 1426173-86-5

Formula: C₂₅H₂₈D₄F₃N₃O₄

Color and Shape: White To Off-White Solid

Molecular weight: 499.57

Ref: 4Z-S-252

Silodosin Impurity 16

CAS: 1426173-86-5

Formula: C₂₅H₃₀F₃N₃O₃

Color and Shape: White To Off-White Solid

Molecular weight: 477.53

Ref: 4Z-S-2526

Silodosin Impurity 13 HCl

CAS: 1426173-86-5

Formula: C₂₂H₂₄F₃N₃O₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 435.45 36.46

Ref: 4Z-S-2523

Silodosin-d4

Controlled Product

CAS: 1426173-86-5

Formula: C₂₅D₄H₂₈F₃N₃O₄

Color and Shape: Neat

Molecular weight: 499.559

Ref: TR-S465001

Silodosin-d4

CAS: 1426173-86-5

Silodosin-d4 is a potent inhibitor that has been used in the treatment of cancer. It is an analog of silodosin, which acts as a kinase inhibitor and induces apoptosis in cancer cells. Silodosin-d4 has been shown to inhibit the activity of the protein kinase C (PKC) family, which are involved in tumor growth and progression. It also inhibits the activity of other kinases such as mitogen-activated protein kinase (MAPK), AKT, and extracellular signal-regulated kinase (ERK). In Chinese medicinal practices, silodosin-d4 has been used as an anticancer agent due to its ability to induce apoptosis and inhibit tumor growth. Silodosin-d4 can be detected in human urine after administration of iloprost, a prostacyclin analogue commonly used for pulmonary hypertension therapy.

Formula: C₂₅H₃₂F₃N₃O₄

Purity: Min. 95%

Molecular weight: 499.6 g/mol

Ref: 3D-BHC17386