CAS 142629-81-0
:3'-azidothymidine-5'-(phenylmethoxyalanyl)phosphate
Description:
3'-Azidothymidine-5'-(phenylmethoxyalanyl)phosphate, also known by its CAS number 142629-81-0, is a nucleotide analog that incorporates an azido group at the 3' position of the thymidine moiety. This compound is characterized by its ability to mimic natural nucleotides, which makes it of interest in biochemical research, particularly in the study of nucleic acid synthesis and antiviral therapies. The presence of the phenylmethoxyalanyl group enhances its stability and solubility, potentially improving its bioavailability. As a phosphate derivative, it is also involved in various biochemical pathways, including those related to phosphorylation processes. The azido group can participate in click chemistry reactions, making this compound useful for bioconjugation applications. Overall, its unique structural features and functional groups contribute to its potential utility in medicinal chemistry and molecular biology.
Formula:C20H25N6O8P
InChI:InChI=1/C20H25N6O8P/c1-12-10-26(20(29)22-18(12)27)17-9-15(23-25-21)16(33-17)11-32-35(30,24-13(2)19(28)31-3)34-14-7-5-4-6-8-14/h4-8,10,13,15-17H,9,11H2,1-3H3,(H,24,30)(H,22,27,29)/t13-,15?,16?,17?,35?/m0/s1
SMILES:Cc1cn(C2CC(C(COP(=O)(N[C@@H](C)C(=O)OC)Oc3ccccc3)O2)N=[N+]=[NH-])c(=O)nc1O
Synonyms:- Azt-pmap
- N-(3'-Azido-3'-deoxy-P-phenyl-5'-thymidylyl)-L-alanine methyl ester
- L-Alanine, N-(3'-azido-3'-deoxy-P-phenyl-5'-thymidylyl)-, methyl ester
- methyl (2S)-2-{[{[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name)
- methyl (2S)-2-{[{[3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name)
- 3'-Azidothymidine-5'-(phenylmethoxyalanyl)phosphate
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Found 1 products.
Azt-pmap
CAS:<p>AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].</p>Formula:C20H25N6O8PPurity:98%Color and Shape:SolidMolecular weight:508.42
