PACE4 Inhibitory peptide C23, identified by its CAS number 1426656-94-1, is a synthetic peptide designed to inhibit the activity of the proprotein convertase enzyme PACE4. This peptide is characterized by its specific amino acid sequence, which is engineered to bind to the active site of the enzyme, thereby preventing substrate cleavage. The inhibition of PACE4 is significant in various biological processes, including protein maturation and processing, which can have implications in cellular signaling and disease mechanisms. The peptide's stability, solubility, and bioavailability are critical factors that influence its efficacy as an inhibitor. Additionally, PACE4 Inhibitory peptide C23 may be utilized in research settings to study the role of PACE4 in physiological and pathological conditions, including cancer and neurodegenerative diseases. Its potential therapeutic applications are under investigation, making it a subject of interest in the fields of biochemistry and pharmacology.

PACE4 Inhibitory peptide C23

1426656-94-1: PACE4 Inhibitory peptide C23, identified by its CAS number 1426656-94-1, is a synthetic peptide designed to inhibit the activity of the proprotein convertase enzyme PACE4. This peptide is characterized by its specific amino acid sequence, which is engineered to bind to the active site of the enzyme, thereby preventing substrate cleavage. The inhibition of PACE4 is significant in various biological processes, including protein maturation and processing, which can have implications in cellular signaling and disease mechanisms. The peptide's stability, solubility, and bioavailability are critical factors that influence its efficacy as an inhibitor. Additionally, PACE4 Inhibitory peptide C23 may be utilized in research settings to study the role of PACE4 in physiological and pathological conditions, including cancer and neurodegenerative diseases. Its potential therapeutic applications are under investigation, making it a subject of interest in the fields of biochemistry and pharmacology.

<p>PACE4 Inhibitory peptide C23 (Compound C23) is an effective peptidomimetic inhibitor known to act against PACE4. It exhibits antiproliferative effects on PCa cell lines, with a Ki of 5 nM, and IC50 values of 25 μM and 40 μM for DU145 and LNCaP cells, respectively. Additionally, PACE4 Inhibitory peptide C23 suppresses tumor growth in LNCaP xenograft mice.</p>

CAS 1426656-94-1

PACE4 Inhibitory peptide C23

PACE4 Inhibitory peptide C23

Ref: TM-TP3027