CAS 14267-92-6

5-Chloro-1-pentyne

Description:

5-Chloro-1-pentyne is an organic compound characterized by its alkyne functional group, specifically a terminal alkyne due to the presence of a triple bond between the first and second carbon atoms in the pentane chain. The "5-chloro" designation indicates that a chlorine atom is substituted at the fifth carbon of the pentyl chain. This compound is typically a colorless to pale yellow liquid with a distinct odor. It is known for its reactivity, particularly in nucleophilic substitution reactions due to the presence of the chlorine atom, which can be replaced by various nucleophiles. 5-Chloro-1-pentyne is also used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Its physical properties include a relatively low boiling point and moderate solubility in organic solvents, while being less soluble in water. Safety precautions are necessary when handling this compound, as it may pose health risks through inhalation or skin contact.

Formula: C₅H₇Cl

InChI: InChI=1S/C5H7Cl/c1-2-3-4-5-6/h1H,3-5H2

InChI key: InChIKey=UXFIKVWAAMKFQE-UHFFFAOYSA-N

SMILES: C(CCCl)C#C

Synonyms:

• (3-Chloropropyl)acetylene
• 1-Chloro-4-pentyne
• 1-Pentyne, 5-chloro-
• 4-Pentynyl chloride
• 5-Chloro-1-Pentyne

5-Chloro-1-pentyne

CAS: 14267-92-6

Formula: C₅H₇Cl

Purity: >96.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 102.56

Ref: 3B-C1522

5-Chloro-1-pentyne

CAS: 14267-92-6

Formula: C₅H₇Cl

Purity: 97%

Color and Shape: Liquid

Molecular weight: 102.5621

Ref: IN-DA00348Q

5-Chloropent-1-yne

CAS: 14267-92-6

5-Chloropent-1-yne

Formula: C₅H₇Cl

Purity: 98%

Color and Shape: clear. colourless liquid

Molecular weight: 102.56g/mol

Ref: 54-OR14511

5-Chloro-1-pentyne

CAS: 14267-92-6

Formula: C₅H₇Cl

Purity: 96%

Color and Shape: Clear light yellow liquid

Molecular weight: 102.56

Ref: 10-F120900

5-Chloropent-1-yne

Controlled Product

CAS: 14267-92-6

Applications 5-Chloropent-1-yne is an intermediate in the synthesis of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995)

Formula: C₅H₇Cl

Color and Shape: Neat

Molecular weight: 102.56

Ref: TR-C375095

5-Chloro-1-pentyne, 98%

CAS: 14267-92-6

5-Chloro-1-pentyne is used with -diazoesters in a copper-catalyzed synthesis of pyrazoles. It is also used in the synthesis of 5-chloro-2-trimethylstannyl-1-pentene by reacting with Me3SnCu.Me2S. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio.

Formula: C₅H₇Cl

Purity: 98%

Color and Shape: Liquid, Clear colorless to pale yellow

Molecular weight: 102.56

Ref: 02-L02835