CAS 14270-73-6

1-(2-deoxy-5-O-tritylpentofuranosyl)pyrimidine-2,4(1H,3H)-dione

Description:

1-(2-Deoxy-5-O-tritylpentofuranosyl)pyrimidine-2,4(1H,3H)-dione is a chemical compound that belongs to the class of nucleoside analogs, which are often utilized in biochemical and pharmaceutical research. This substance features a pyrimidine ring, which is a six-membered aromatic ring containing nitrogen atoms, and is substituted with a deoxypentofuranosyl moiety, indicating that it is a derivative of ribose sugar lacking an oxygen atom at the 2' position. The presence of the trityl group (a bulky aromatic protecting group) at the 5' position suggests that this compound is designed for stability and protection against hydrolysis, which is crucial for nucleoside analogs. The compound exhibits properties typical of nucleobases, including potential interactions with nucleic acids, and may have implications in the development of antiviral or anticancer agents. Its unique structure allows for specific interactions in biological systems, making it a subject of interest in medicinal chemistry and molecular biology.

Formula: C₂₈H₂₆N₂O₅

InChI: InChI=1/C28H26N2O5/c31-23-18-26(30-17-16-25(32)29-27(30)33)35-24(23)19-34-28(20-10-4-1-5-11-20,21-12-6-2-7-13-21)22-14-8-3-9-15-22/h1-17,23-24,26,31H,18-19H2,(H,29,32,33)

SMILES: c1ccc(cc1)C(c1ccccc1)(c1ccccc1)OCC1C(CC(n2ccc(nc2=O)O)O1)O

Synonyms:

• 2,4(1H,3H)-pyrimidinedione, 1-[2-deoxy-5-O-(triphenylmethyl)pentofuranosyl]-
• 5'-O-Trityl-2'-Deoxyuridine

5'-O-Trityl-2'-deoxyuridine

CAS: 14270-73-6

Formula: C₂₈H₂₆N₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 470.5164

Ref: IN-DA007KRZ

1-((2R,4S,5R)-4-Hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 14270-73-6

1-((2R,4S,5R)-4-Hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Purity: 95%

Molecular weight: 470.53g/mol

Ref: 54-OR1052575

5'-O-Triphenylmethyl-2'-deoxyuridine

CAS: 14270-73-6

5'-O-Triphenylmethyl-2'-deoxyuridine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.

Formula: C₂₈H₂₆N₂O₅

Color and Shape: Solid

Molecular weight: 470.52

Ref: TM-TNU1518

2'-Deoxy-5'-O-trityluridine

CAS: 14270-73-6

2'-Deoxy-5'-O-trityluridine is a nucleoside that has been synthesized for visualization purposes. It is an analog of uridine, with the structure shown in Figure 1. The trityl group is oriented on the 2' oxygen atom, which is attached to the ribose sugar. This configuration allows for a variety of interactions with other molecules and can be seen in Figure 2. The methyl group on the 5' carbon atom interacts with the benzene ring on xylene, while the moiety on the 3' carbon atom interacts with furanose. This nucleoside also has a symmetric conformation, as shown in Figure 3.

Formula: C₂₈H₂₆N₂O₅

Purity: Min. 95%

Molecular weight: 470.52 g/mol

Ref: 3D-NT08746