Erythromycin hydrochloride is a macrolide antibiotic derived from the bacterium Saccharopolyspora erythraea. It is primarily used to treat various bacterial infections, particularly those caused by Gram-positive bacteria and some Gram-negative bacteria. The compound is characterized by its ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit, effectively blocking the translocation of peptides. Erythromycin hydrochloride is typically administered orally or intravenously and is known for its relatively low toxicity. It is soluble in water and exhibits a pH-dependent solubility profile, which can influence its absorption and bioavailability. The substance is also sensitive to acid degradation, necessitating careful formulation in pharmaceutical preparations. Common side effects may include gastrointestinal disturbances, such as nausea and diarrhea. Erythromycin's spectrum of activity includes respiratory tract infections, skin infections, and certain sexually transmitted infections, making it a versatile option in clinical settings. Additionally, it is important to consider potential drug interactions, as erythromycin can affect the metabolism of various medications due to its influence on cytochrome P450 enzymes.

Erythromycin,hydrochloride (8CI,9CI)

14271-02-4: Erythromycin hydrochloride is a macrolide antibiotic derived from the bacterium Saccharopolyspora erythraea. It is primarily used to treat various bacterial infections, particularly those caused by Gram-positive bacteria and some Gram-negative bacteria. The compound is characterized by its ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit, effectively blocking the translocation of peptides. Erythromycin hydrochloride is typically administered orally or intravenously and is known for its relatively low toxicity. It is soluble in water and exhibits a pH-dependent solubility profile, which can influence its absorption and bioavailability. The substance is also sensitive to acid degradation, necessitating careful formulation in pharmaceutical preparations. Common side effects may include gastrointestinal disturbances, such as nausea and diarrhea. Erythromycin's spectrum of activity includes respiratory tract infections, skin infections, and certain sexually transmitted infections, making it a versatile option in clinical settings. Additionally, it is important to consider potential drug interactions, as erythromycin can affect the metabolism of various medications due to its influence on cytochrome P450 enzymes.

<p>Erythromycin hydrochloride is an inhibitor of protein translation and mammalian mRNA splicing. It inhibits growth of gram negative and gram positiove bacteria.</p>

CAS 14271-02-4

Erythromycin,hydrochloride (8CI,9CI)

Erythromycin hydrochloride

Ref: TM-T70696