CAS 1427177-15-8

Dechlorodehydrogriseofulvin

Description:

Dechlorodehydrogriseofulvin is a synthetic derivative of griseofulvin, which is an antifungal agent originally derived from the mold Penicillium griseofulvum. This compound is characterized by its structural modifications that enhance its pharmacological properties. It typically exhibits antifungal activity, making it relevant in the treatment of dermatophyte infections. The chemical structure of Dechlorodehydrogriseofulvin includes a modified lactone ring and altered substituents that contribute to its efficacy and bioavailability. It is generally studied for its mechanism of action, which involves disrupting fungal cell division by inhibiting mitosis. Additionally, the compound may possess varying solubility and stability profiles compared to its parent compound, influencing its formulation and delivery methods. As with many pharmaceuticals, safety and toxicity profiles are critical, and ongoing research may explore its potential applications in other therapeutic areas. Overall, Dechlorodehydrogriseofulvin represents a significant advancement in antifungal therapy, with a focus on improving treatment outcomes for fungal infections.

Formula: C₁₇H₁₆O₆

InChI: InChI=1S/C17H16O6/c1-9-5-10(18)6-14(22-4)17(9)16(19)15-12(21-3)7-11(20-2)8-13(15)23-17/h5-8H,1-4H3/t17-/m0/s1

InChI key: InChIKey=CHQXBZFVCIIBRO-KRWDZBQOSA-N

SMILES: O=C1[C@]2(C(OC)=CC(=O)C=C2C)OC=3C1=C(OC)C=C(OC)C3

Synonyms:

• 7-Dechlorodehydrogriseofulvin
• (1′S)-2′,4,6-Trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2,5]cyclohexadiene]-3,4′-dione
• Spiro[benzofuran-2(3H),1′-[2,5]cyclohexadiene]-3,4′-dione, 2′,4,6-trimethoxy-6′-methyl-, (1′S)-
• Dechlorodehydrogriseofulvin

Dechloro Dehydro Griseofulvin

CAS: 1427177-15-8

Formula: C₁₇H₁₆O₆

Molecular weight: 316.31

Ref: 4Z-G-089