CAS 142761-12-4

S-(+)-O-DESMETHYLVENLAFAXINE

Description:

S-(+)-O-Desmethylvenlafaxine, with the CAS number 142761-12-4, is a chemical compound that serves as a metabolite of venlafaxine, an antidepressant medication. This substance is characterized by its chiral nature, possessing a specific stereochemistry that contributes to its pharmacological activity. It is primarily recognized for its role as a serotonin-norepinephrine reuptake inhibitor (SNRI), which enhances the levels of neurotransmitters in the brain, thereby potentially improving mood and alleviating symptoms of depression and anxiety. The compound is typically found in the form of a white to off-white solid and is soluble in organic solvents. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are influenced by its chemical structure. As a metabolite, S-(+)-O-desmethylvenlafaxine may also exhibit its own therapeutic effects and side effects, which are important considerations in clinical settings. Overall, this compound plays a significant role in the pharmacological profile of venlafaxine and is of interest in both medicinal chemistry and therapeutic applications.

Formula: C₁₆H₂₅NO₂

InChI: InChI=1/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3/t15-/m1/s1

SMILES: CN(C)C[C@H](c1ccc(cc1)O)C1(CCCCC1)O

Synonyms:

• 4-[(1S)-2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol

(S)-O-Desmethyl-Venlafaxine

CAS: 142761-12-4

Formula: C₁₆H₂₅NO₂

Color and Shape: White To Off-White Solid

Molecular weight: 263.38

Ref: 4Z-V-0325

S-(+)-O-Desmethyl Venlafaxine

CAS: 142761-12-4

Applications A metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant.Also used as high-dose venlafaxine treatment in depressed patient with a genetic CYP2D6 deficiency.
References Haller-G., et al.: Int. J. Psychiatry Clin. Pract., 8, 191 (2004)

Formula: C₁₆H₂₅NO₂

Color and Shape: Neat

Molecular weight: 263.38

Ref: TR-D296510

Desvenlafaxine S-Isomer

CAS: 142761-12-4

Formula: C₁₆H₂₅NO₂

Molecular weight: 263.4

Ref: ST-EA-CP-D16010

(S)-O-Desmethyl-Venlafaxine

CAS: 142761-12-4

Formula: C₁₆H₂₅NO₂

Molecular weight: 263.38

Ref: ST-EA-CP-V2065