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CAS 142810-18-2

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Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-isoleucyl-

Description:
Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-isoleucyl-, commonly referred to as Fmoc-L-isoleucine, is a derivative of the amino acid isoleucine, modified with a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is characterized by its role in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective moiety for the amino group, allowing for selective coupling reactions. The presence of the fluorenyl group contributes to the compound's stability and solubility in organic solvents, facilitating its use in various synthetic applications. Fmoc-L-isoleucine is typically a white to off-white solid and is soluble in polar organic solvents. Its molecular structure includes a central isoleucine backbone, with the Fmoc group providing steric hindrance that aids in the selective deprotection of the amino group during synthesis. This compound is essential in the field of biochemistry and pharmaceutical development, particularly in the design and synthesis of peptides and proteins.
Formula:C23H26N2O5
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