Description:2-Bromo-3-methylthiophene is a heterocyclic organic compound characterized by a five-membered aromatic ring containing both sulfur and bromine substituents. The structure consists of a thiophene ring, which is a sulfur-containing analog of furan, with a bromine atom attached to the second carbon and a methyl group at the third carbon position. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is known for its reactivity due to the presence of the bromine atom, which can participate in various substitution reactions, making it useful in organic synthesis. The methylthio group contributes to its unique electronic properties, influencing its reactivity and solubility in organic solvents. 2-Bromo-3-methylthiophene is utilized in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals, and its properties can be affected by factors such as temperature and solvent choice. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested.
Applications 2-Bromo-3-methylthiophene is used to prepare pyrazolo[3,4-d]pyrimidine derivatives as inhibitors of human enterovirus, coxsackievirus, echovirus, …
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