CAS 14282-76-9

2-Bromo-3-methylthiophene

Description:

2-Bromo-3-methylthiophene is a heterocyclic organic compound characterized by a five-membered aromatic ring containing both sulfur and bromine substituents. The structure consists of a thiophene ring, which is a sulfur-containing analog of furan, with a bromine atom attached to the second carbon and a methyl group at the third carbon position. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is known for its reactivity due to the presence of the bromine atom, which can participate in various substitution reactions, making it useful in organic synthesis. The methylthio group contributes to its unique electronic properties, influencing its reactivity and solubility in organic solvents. 2-Bromo-3-methylthiophene is utilized in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals, and its properties can be affected by factors such as temperature and solvent choice. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested.

Formula: C₅H₅BrS

InChI: InChI=1S/C5H5BrS/c1-4-2-3-7-5(4)6/h2-3H,1H3

InChI key: InChIKey=YYJBWYBULYUKMR-UHFFFAOYSA-N

SMILES: CC1=C(Br)SC=C1

Synonyms:

• 2B3Mt
• 5-Bromo-4-methylthiophene
• Thiophene, 2-bromo-3-methyl-
• 2-Bromo-3-methylthiophene

2-Bromo-3-methylthiophene

CAS: 14282-76-9

Formula: C₅H₅BrS

Purity: >98.0%(GC)

Color and Shape: White - Yellow Liquid

Molecular weight: 177.06

Ref: 3B-B1025

2-Bromo-3-methylthiophene, 97%

CAS: 14282-76-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₅H₅BrS

Purity: 97%

Color and Shape: Clear, colorless to yellow or orange, Liquid

Molecular weight: 177.06

Ref: 02-L11393

2-Bromo-3-methylthiophene

CAS: 14282-76-9

Formula: C₅H₅BrS

Purity: 95%

Color and Shape: Liquid

Molecular weight: 177.0622

Ref: IN-DA003GN6

2-Bromo-3-methylthiophene

CAS: 14282-76-9

2-Bromo-3-methylthiophene

Formula: C₅H₅BrS

Purity: 97%

Color and Shape: clear. pale yellow liquid

Molecular weight: 177.06g/mol

Ref: 54-OR8041

2-Bromo-3-methylthiophene

CAS: 14282-76-9

Formula: C₅H₅BrS

Purity: 95%

Color and Shape: Liquid

Molecular weight: 177.06

Ref: 10-F013451

2-Bromo-3-methylthiophene

CAS: 14282-76-9

2-Bromo-3-methylthiophene (2BMT) is an organic chemical compound that has been used for the Suzuki coupling reaction. It can be prepared by reacting 2-bromo-3-methylthiophene with potassium hydroxide in a hydroxide solution. 2BMT has shown to inhibit the activity of tiagabine hydrochloride, which is a drug that regulates GABA neurotransmission. 2BMT is also used as an intermediate in the synthesis of carbonyl group compounds and halides. The structure and physical properties of 2BMT have been studied in detail by x-ray crystallography and nmr spectroscopy.

Formula: C₅H₅BrS

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 177.06 g/mol

Ref: 3D-FB03109

2-Bromo-3-methylthiophene

Controlled Product

CAS: 14282-76-9

Applications 2-Bromo-3-methylthiophene is used to prepare pyrazolo[3,4-d]pyrimidine derivatives as inhibitors of human enterovirus, coxsackievirus, echovirus, influenza virus, herpes simplex virus and rhinovirus. It is also used in the synthesis of oral α7 nicotinic receptor agonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chern, J., et al.: Bioorg. Med. Chem. Lett., 14, 2519 (2004); Tatsumi, R., et al.: J. Med. Chem., 48, 2678 (2005)

Formula: C₅H₅BrS

Color and Shape: Neat

Molecular weight: 177.06

Ref: TR-B685785