CAS 142926-86-1

homoanatoxin

Description:

Homoanatoxin, identified by its CAS number 142926-86-1, is a potent neurotoxin produced by certain cyanobacterial species, particularly those in the genera Anabaena and Aphanizomenon. This compound is structurally related to anatoxin-a, another well-known neurotoxin, and exhibits similar mechanisms of action by binding to nicotinic acetylcholine receptors, leading to overstimulation of the nervous system. Homoanatoxin is characterized by its high toxicity, which can result in severe neurological effects in exposed organisms, including paralysis and potentially death. It is typically found in freshwater environments, especially during algal blooms, and poses significant risks to aquatic life and animals that consume contaminated water. Due to its toxic nature, monitoring and management of water bodies for the presence of homoanatoxin are crucial for public health and environmental safety. Its stability in various environmental conditions can complicate remediation efforts, making it a subject of ongoing research in toxicology and environmental science.

Formula: C₁₁H₁₇NO

InChI: InChI=1/C11H17NO/c1-2-11(13)9-5-3-4-8-6-7-10(9)12-8/h5,8,10,12H,2-4,6-7H2,1H3/t8-,10-/m0/s1

SMILES: CCC(=O)C1=CCC[C@H]2CC[C@@H]1N2

Synonyms:

• (1R)-1-(9-Azabicyclo(4.2.1)non-2-en-2-yl)-1-propanone
• 2-(Propan-1-oxo-1-yl)-9-azabicyclo(4.2.1)non-2-ene
• Homoantx
• 1-Propanone, 1-(9-azabicyclo(4.2.1)non-2-en-2-yl)-, (1R)-
• 1-[(1S,6S)-9-azabicyclo[4.2.1]non-2-en-2-yl]propan-1-one
• Homoanatoxin

(R,R)-(+)-Homoanatoxin A

CAS: 142926-86-1

Formula: C₁₁H₁₇NO

Molecular weight: 179.26

Ref: 4Z-A-371002

(R,R)-(+)-Homoanatoxin A hydrochloride

CAS: 142926-86-1

(R,R)-(+)-Homoanatoxin A hydrochloride is a potent inhibitor of protein phosphatases and has been shown to induce apoptosis in human cell lines. It has potential as an anticancer agent due to its ability to inhibit the growth and proliferation of cancer cells by inducing cell cycle arrest and cell death. This compound has been isolated from Chinese medicinal herbs and has shown promising results in inhibiting tumor growth in animal models. Additionally, (R,R)-(+)-Homoanatoxin A hydrochloride can be detected in urine samples of cancer patients, suggesting its potential as a biomarker for cancer diagnosis and monitoring treatment efficacy. Overall, this compound shows great promise as a novel therapeutic agent for the treatment of various types of cancers.

Formula: C₁₁H₁₇NO•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 215.72 g/mol

Ref: 3D-SFA92686

(R,R)-(+)-Homoanatoxin a (Propionyl-d3) Hydrochloride

Controlled Product

CAS: 142926-85-0, 142926-86-1

Formula: C₁₁H₁₄D₃NO·HCl

Color and Shape: Neat

Molecular weight: 218.74

Ref: TR-H459102

(R,R)-(+)-Homoanatoxin A (Hydrochloride)

Controlled Product

CAS: 142926-85-0, 142926-86-1

Formula: C₁₁H₁₇NO·HCl

Color and Shape: Neat

Molecular weight: 215.72

Ref: TR-H459100