CAS 14293-44-8
:Xipamide
Description:
Xipamide is a thiazide-like diuretic medication primarily used to treat hypertension and edema associated with heart failure or renal disorders. It functions by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased urine output and decreased blood volume. Xipamide is characterized by its chemical structure, which includes a sulfonamide group, contributing to its diuretic properties. It is typically administered orally and has a moderate onset of action, with effects lasting for several hours. The substance is known for its relatively low solubility in water, which can influence its bioavailability and absorption. Additionally, xipamide may have interactions with other medications and can cause side effects such as electrolyte imbalances, particularly hypokalemia. Monitoring of renal function and electrolyte levels is recommended during treatment. Overall, xipamide is an effective agent in managing fluid retention and hypertension, with a well-established profile in clinical use.
Formula:C15H15ClN2O4S
InChI:InChI=1S/C15H15ClN2O4S/c1-8-4-3-5-9(2)14(8)18-15(20)10-6-13(23(17,21)22)11(16)7-12(10)19/h3-7,19H,1-2H3,(H,18,20)(H2,17,21,22)
InChI key:InChIKey=MTZBBNMLMNBNJL-UHFFFAOYSA-N
SMILES:C(NC1=C(C)C=CC=C1C)(=O)C2=CC(S(N)(=O)=O)=C(Cl)C=C2O
Synonyms:- 238-216-4
- 2′,6′-Salicyloxylidide, 4-chloro-5-sulfamoyl-
- 4-Chloro-5-sulfamylsalicyloyl-2',6'-dimethylanilide
- 4-Chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
- 5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxybenzamide
- Aquaphor
- Aquaphor (diuretic)
- Be 1293
- Bei 1293
- Chronexan
- Diurex
- Diurex (Lacer)
- Diurexan
- Lumitens
- Mjf 10938
- benzamide, 5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 11 products.
Benzamide,5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-
CAS:Formula:C15H15ClN2O4SPurity:98%Color and Shape:SolidMolecular weight:354.80864-Chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulphamoylbenzamide
CAS:<p>4-Chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulphamoylbenzamide</p>Purity:97%Molecular weight:354.81g/molXipamide
CAS:Controlled Product<p>Applications Xipamide is a diuretic and antihypertensive agent.<br>References Wagieh, N., et al.: Drug Test. Anal., 2, 113 (2010), Prado-Prado, F., et al.: Bioorg. Med. Chem., 18, 2225 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Formula:C15H15ClN2O4SColor and Shape:NeatMolecular weight:354.81Xipamide
CAS:Controlled Product<p>Xipamide is a dpp-iv inhibitor that functions by blocking the enzyme dipeptidyl peptidase IV (dpp-iv). Xipamide inhibits the production of proinflammatory cytokines such as tumor necrosis factor alpha (TNF-α) and interleukin 1 beta (IL-1β) in vitro. It is also effective against infectious diseases, including bacterial infections, respiratory tract infections, and skin infections. Xipamide has been shown to be safe for use in geriatric patients with congestive heart failure. The optimum concentration for xipamide is 0.4 μM. Xipamide has been used to study biological processes such as signal transduction, cell proliferation, and apoptosis in vitro. Optical sensor technology has been applied to examine the stability of this drug in human serum and its potential interactions with surfactant sodium dodecyl sulfate (SDS).</p>Formula:C15H15ClN2O4SPurity:Min. 95%Color and Shape:White PowderMolecular weight:354.81 g/molXipamide
CAS:Formula:C15H15ClN2O4SPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:354.814-Chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
CAS:Formula:C15H15ClN2O4SPurity:95.0%Color and Shape:SolidMolecular weight:354.81Xipamide
CAS:<p>Xipamide (Diurexan) is a sulfonamide-based diuretic with antihypertensive properties. Xipamide selectively inhibits anion exchanger.</p>Formula:C15H15ClN2O4SPurity:99.91%Color and Shape:SolidMolecular weight:354.81
