CAS 1429882-07-4

UNC-2371A

Description:

As of my last update in October 2023, there is limited publicly available information regarding the chemical substance UNC-2371A, identified by the CAS number 1429882-07-4. This compound is primarily recognized in the context of research, particularly in the field of medicinal chemistry and pharmacology. UNC-2371A is known to be a selective inhibitor of certain biological targets, which may include specific enzymes or receptors involved in various physiological processes. Its structure and properties may suggest potential applications in therapeutic areas, although detailed characteristics such as solubility, stability, and specific biological activity are typically found in specialized scientific literature or proprietary databases. Researchers interested in this compound would likely need to consult peer-reviewed studies or chemical databases for comprehensive data, including synthesis methods, safety profiles, and experimental results related to its efficacy and mechanism of action.

Formula: C₂₉H₄₀N₆O

Synonyms:

• UNC-2371A
• Cyclohexanol, 4-[2-[(2-cyclopropylethyl)amino]-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-, trans-
• UNC2371;MRX-2843
• MRX-2843 (UNC2371)
• MRX-2843
• UNC2371
• (1r,4r)-4-(2-(2-cyclopropylethylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol
• MRX-2843?(Synonyms: UNC2371

MRX-2843

CAS: 1429882-07-4

MRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).

Formula: C₂₉H₄₀N₆O

Purity: 98.59% - 99.63%

Color and Shape: Solid

Molecular weight: 488.67

Ref: TM-T16144

MRX-2843

CAS: 1429882-07-4

MRX-2843

Purity: ≥98%

Molecular weight: 488.67g/mol

Ref: 54-BUP05446

MRX-2843-d8

CAS: 1429882-07-4

Formula: C₂₉H₃₂D₈N₆O

Molecular weight: 496.73

Ref: 4Z-M-232002

MRX-2843

CAS: 1429882-07-4

Formula: C₂₉H₄₀N₆O

Molecular weight: 488.68

Ref: 4Z-M-232001

MRX-2843

Controlled Product

CAS: 1429882-07-4

Applications MRX-2843, is an orally available small-molecule inhibitor of both MERTK and FLT3.
References Minson, K. A. et al.: JCI Insight. 2016 Mar;1(3):e85630.;

Formula: C₂₉H₄₀N₆O

Color and Shape: Neat

Molecular weight: 488.67

Ref: TR-M750145

MRX-2843

CAS: 1429882-07-4

MRX-2843 is a small molecule that inhibits the tyrosine kinase activity of Flt3. Flt3 is a receptor tyrosine kinase which plays an important role in T-cell leukemia, autoimmune diseases, and inflammation. MRX-2843 also has anti-infective properties and can be used to treat bacterial infections such as tuberculosis. In preclinical studies MRX-2843 was shown to inhibit the growth of cancer cells in cell culture and xenograft models. It also showed efficacy against wild-type mice with leukemia when administered orally or intravenously, but not when given topically.

Formula: C₂₉H₄₀N₆O

Purity: Min. 95%

Molecular weight: 488.67 g/mol

Ref: 3D-EHC88207