CAS 142997-31-7

Suc-Ala-Leu-Pro-Phe-AMC

Description:

Suc-Ala-Leu-Pro-Phe-AMC, also known as a peptide substrate, is a synthetic compound commonly used in biochemical research, particularly in studies involving proteases and enzyme activity. This compound consists of a sequence of amino acids, specifically succinylated alanine, leucine, proline, and phenylalanine, linked to an AMC (7-amino-4-methylcoumarin) fluorophore. The succinyl group enhances the solubility and stability of the peptide, while the AMC moiety serves as a fluorescent tag that allows for the detection of enzymatic cleavage. Upon hydrolysis by specific proteases, the AMC group is released, resulting in an increase in fluorescence, which can be quantitatively measured. This property makes Suc-Ala-Leu-Pro-Phe-AMC a valuable tool for studying enzyme kinetics and protease specificity. The compound is typically used in laboratory settings and is not intended for therapeutic use. Its stability, specificity, and fluorescent properties make it an essential reagent in proteomics and enzymology research.

Formula: C₃₇H₄₅N₅O₉

Synonyms:

• Suc-Alpf-Amc
• Suc-Ala-Leu-Pro-Phe-7-Amino-4-Methylcoumarin
• Peptidylprolyl Isomerase Fluorogenic Substrate (Suc-Alpf-Amc)
• Pplase Substrate Ii, Fluorogenic

Suc-Ala-Leu-Pro-Phe-Amc

Controlled Product

CAS: 142997-31-7

Formula: C₃₇H₄₅N₅O₉

Color and Shape: Neat

Molecular weight: 703.781

Ref: TR-S688130

Suc-Ala-Leu-Pro-Phe-AMC tfluoroacetic acid

CAS: 142997-31-7

Suc-Ala-Leu-Pro-Phe-AMC tfluoroacetic acid is a synthetic peptide that has been shown to have the ability to inhibit the function of an enzyme called isomerase. It binds to the catalytic region of the enzyme and blocks its activity, which prevents the production of amino acid molecules. Suc-Ala-Leu-Pro-Phe-AMC tfluoroacetic acid also has immunosuppressive properties, which are due to its ability to bind to regulatory domains in cells and prevent their transcriptional activation. This molecule also has a catalytic function and can be used as a building block for synthesizing other molecules with similar functions.

Formula: C₃₇H₄₅N₅O₉•xCF₃CO₂H

Purity: Min. 95%

Molecular weight: 703.78 g/mol

Ref: 3D-FS110573