G-CSF, or Granulocyte Colony-Stimulating Factor, is a glycoprotein that plays a crucial role in hematopoiesis, specifically in the stimulation of the production and differentiation of neutrophil precursors in the bone marrow. It is primarily produced by macrophages, endothelial cells, and fibroblasts in response to inflammatory stimuli. G-CSF functions by binding to its receptor, which activates signaling pathways that promote the proliferation and survival of neutrophil progenitor cells. This factor is clinically significant, particularly in the context of chemotherapy, where it is used to mitigate neutropenia, a condition characterized by low neutrophil counts. G-CSF is administered as a recombinant protein and has been shown to enhance the recovery of white blood cells after myelosuppressive treatments. Additionally, it has applications in mobilizing stem cells for transplantation. The CAS number 143011-72-7 specifically identifies a synthetic form of G-CSF, which is utilized in various therapeutic settings. Overall, G-CSF is a vital component in managing immune responses and supporting recovery in patients undergoing intensive medical treatments.

G-CSF

143011-72-7: G-CSF, or Granulocyte Colony-Stimulating Factor, is a glycoprotein that plays a crucial role in hematopoiesis, specifically in the stimulation of the production and differentiation of neutrophil precursors in the bone marrow. It is primarily produced by macrophages, endothelial cells, and fibroblasts in response to inflammatory stimuli. G-CSF functions by binding to its receptor, which activates signaling pathways that promote the proliferation and survival of neutrophil progenitor cells. This factor is clinically significant, particularly in the context of chemotherapy, where it is used to mitigate neutropenia, a condition characterized by low neutrophil counts. G-CSF is administered as a recombinant protein and has been shown to enhance the recovery of white blood cells after myelosuppressive treatments. Additionally, it has applications in mobilizing stem cells for transplantation. The CAS number 143011-72-7 specifically identifies a synthetic form of G-CSF, which is utilized in various therapeutic settings. Overall, G-CSF is a vital component in managing immune responses and supporting recovery in patients undergoing intensive medical treatments.

CAS 143011-72-7

G-CSF

FILGRASTIM CRS

Ref: 41-Y0001173