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CAS 1430219-69-4

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  • RI-OR2-TAT
    Targetmol
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    RI-OR2-TAT

    CAS:
    <p>RI-OR2-TAT is a brain-penetrable inhibitor targeting β-amyloid (β-Amyloid) oligomerization. It is engineered by integrating the HIV protein transduction domain TAT into RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. It reduces Aβ aggregation and plaque levels, diminishes microglial activation and oxidative damage, and enhances the number of young neurons in the dentate gyrus.</p>
    Formula:C117H201N49O23
    Color and Shape:Solid
    Molecular weight:2662.16

    Ref: TM-TP3015