CAS 1431697-74-3

2-[(1S)-1-[(2-Amino-9H-purin-6-yl)amino]ethyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone

Description:

The chemical substance known as 2-[(1S)-1-[(2-Amino-9H-purin-6-yl)amino]ethyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone, with the CAS number 1431697-74-3, is a complex organic compound characterized by its quinazolinone core structure, which is fused with a methyl and a 2-methylphenyl substituent. This compound features an amino group attached to a purine derivative, indicating potential biological activity, particularly in the realm of medicinal chemistry. The presence of multiple functional groups, including amines and aromatic rings, suggests that it may exhibit diverse interactions with biological targets, potentially influencing its pharmacological properties. The stereochemistry indicated by the (1S) configuration suggests specific spatial arrangements that could affect its biological activity and binding affinity. Overall, this compound may be of interest in drug development, particularly in targeting specific pathways or receptors in cellular processes. Further studies would be necessary to elucidate its exact mechanisms of action and therapeutic potential.

Formula: C₂₃H₂₂N₈O

InChI: InChI=1S/C23H22N8O/c1-12-7-4-5-10-16(12)31-21(28-15-9-6-8-13(2)17(15)22(31)32)14(3)27-20-18-19(26-11-25-18)29-23(24)30-20/h4-11,14H,1-3H3,(H4,24,25,26,27,29,30)/t14-/m0/s1

InChI key: InChIKey=PUYVJBBSBPUKBT-AWEZNQCLSA-N

SMILES: [C@H](NC1=C2C(=NC(N)=N1)N=CN2)(C)C=3N(C(=O)C=4C(N3)=CC=CC4C)C5=C(C)C=CC=C5

Synonyms:

• 2-[(1S)-1-[(2-Amino-9H-purin-6-yl)amino]ethyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
• 4(3H)-Quinazolinone, 2-[(1S)-1-[(2-amino-9H-purin-6-yl)amino]ethyl]-5-methyl-3-(2-methylphenyl)-

2-[(1S)-1-[(2-Amino-9H-purin-6-yl)amino]ethyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone

CAS: 1431697-74-3

Formula: C₂₃H₂₂N₈O

Molecular weight: 426.4738

Ref: IN-DA009CA1

2-​[(1S)​-​1-​[(2-​Amino-​9H-​purin-​6-​yl)​amino]​ethyl]​-​5-​methyl-​3-​(2-​methylphenyl)​-4(3H)​-​quinazolinone

CAS: 1431697-74-3

2-((1S)-1-[[2-Amino-9H-purin-6-yl]amino]ethyl)-5-methyl-3-(2-methylphenyl)-4(3H)quinazolinone is a synthetic, high purity, potent and selective agonist at the δ subtype of the GABAA receptor. It has been shown to inhibit calcium influx in cells with no effect on chloride influx.

Formula: C₂₃H₂₂N₈O

Purity: Min. 95%

Molecular weight: 426.5 g/mol

Ref: 3D-GHC69774

CAL-130

CAS: 1431697-74-3

CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).

Formula: C₂₃H₂₂N₈O

Purity: 98%

Color and Shape: Solid

Molecular weight: 426.47

Ref: TM-T10660