CAS 1431980-60-7

TASP 0433864

CAS: 1431980-60-7

TASP 0433864 is a research tool that can be used for cell biology and pharmacology studies. It is an inhibitor of ion channels, ligand-gated ion channels, and receptor-gated ion channels. TASP 0433864 has been shown to inhibit the activation of the GABAA receptor by benzodiazepines in vitro. In addition, it has been shown to have high purity and stability in various solvents (including DMSO). TASP 0433864 is a peptide with a molecular weight of 1270.1 Da and an isoelectric point of 4.7. It binds selectively to the alpha subunit of the nicotinic acetylcholine receptor (nAChR) at a site that is different from that of nicotine or acetylcholine. This binding blocks the binding site for acetylcholinesterase, leading to prolonged activation and increased channel opening probability.

Formula: C₁₈H₂₃N₃O₃

Purity: Min. 95%

Molecular weight: 329.4 g/mol

Ref: 3D-GHC98060

TASP0433864

CAS: 1431980-60-7

TASP0433864 enhances mGlu2 activity; EC50: 199 nM (human), 206 nM (rat); not an agonist.

Formula: C₁₈H₂₃N₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 329.39

Ref: TM-T28928