CAS 143225-31-4

Fosamprenavir Impurity 4

CAS: 143225-31-4

Formula: C₁₉H₃₂N₂O₃

Molecular weight: 336.48

Ref: 4Z-F-159

tert-Butyl ((1S)-1-Hydroxy-1(isobutylamino)-3-phenylpropan-2-yl)carbamate

Controlled Product

CAS: 143225-31-4, 160232-08-6

Applications tert-Butyl ((1S)-1-Hydroxy-1(isobutylamino)-3-phenylpropan-2-yl)carbamate is an protected intermediate in the synthesis of Darunavir (D193500), a second generation HIV-1-protease inhibitor.

Formula: C₁₉H₃₂N₂O₃

Color and Shape: Neat

Molecular weight: 336.469

Ref: TR-B692095

1,1-Dimethylethyl Ester [(1S,2S)-2-Hydroxy-3-[(2-methylpropyl)amino]-1-(phenylmethyl)propyl]carbamic Acid

Controlled Product

CAS: 143225-31-4

Applications 1,1-Dimethylethyl Ester [(1S,2S)-2-Hydroxy-3-[(2-methylpropyl)amino]-1-(phenylmethyl)propyl]carbamic Acid is an intermediate in the synthesis of 2-epi-Darunavir (D193530), which is a stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral.
References Rao, R.N., et. al.: J. Sep. Sci., 35, 2671 (2012); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003); Arasteh, K., et al.: AIDS, 19, 943 (2005); Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005)

Formula: C₁₉H₃₂N₂O₃

Color and Shape: Neat

Molecular weight: 336.47

Ref: TR-D143225