(R)-Azelastine is a chiral compound primarily recognized for its application as an antihistamine, particularly in the treatment of allergic rhinitis and conjunctivitis. It belongs to the class of drugs known as H1 receptor antagonists, which work by blocking the action of histamine, a substance in the body that causes allergic symptoms. The molecular structure of (R)-Azelastine features a central azetidine ring, contributing to its pharmacological activity. It is characterized by its relatively low solubility in water but higher solubility in organic solvents, which influences its formulation in pharmaceutical products. The compound exhibits a long half-life, allowing for once-daily dosing in therapeutic applications. Additionally, (R)-Azelastine has been noted for its rapid onset of action and potential anti-inflammatory properties, making it effective in alleviating symptoms associated with allergic reactions. As with many medications, it is essential to consider its side effects, which may include drowsiness and dry mouth, necessitating caution in certain populations.

(R)-Azelastine

143228-84-6: (R)-Azelastine is a chiral compound primarily recognized for its application as an antihistamine, particularly in the treatment of allergic rhinitis and conjunctivitis. It belongs to the class of drugs known as H1 receptor antagonists, which work by blocking the action of histamine, a substance in the body that causes allergic symptoms. The molecular structure of (R)-Azelastine features a central azetidine ring, contributing to its pharmacological activity. It is characterized by its relatively low solubility in water but higher solubility in organic solvents, which influences its formulation in pharmaceutical products. The compound exhibits a long half-life, allowing for once-daily dosing in therapeutic applications. Additionally, (R)-Azelastine has been noted for its rapid onset of action and potential anti-inflammatory properties, making it effective in alleviating symptoms associated with allergic reactions. As with many medications, it is essential to consider its side effects, which may include drowsiness and dry mouth, necessitating caution in certain populations.

(R)-Azelastine, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.

CAS 143228-84-6

(R)-Azelastine

(R)-Azelastine

Ref: TM-T70675