CAS 143257-98-1: Lerisetron

Description: Lerisetron is a chemical compound classified as a selective serotonin receptor antagonist, specifically targeting the 5-HT3 receptor. It is primarily investigated for its potential use in the treatment of gastrointestinal disorders, particularly those associated with nausea and vomiting, such as chemotherapy-induced nausea. The compound exhibits a high affinity for the 5-HT3 receptor, which plays a crucial role in the emetic response. Lerisetron's mechanism of action involves blocking serotonin's effects at these receptors, thereby reducing the sensation of nausea. In terms of its physical properties, Lerisetron is typically presented as a white to off-white solid, and its solubility characteristics allow for formulation in various pharmaceutical preparations. As with many pharmacological agents, the safety and efficacy profile of Lerisetron is evaluated through clinical trials, and it is essential to consider potential side effects and interactions with other medications. Overall, Lerisetron represents a significant area of research in the field of antiemetic therapies.

Formula: C₁₈H₂₀N₄

InChI: InChI=1S/C18H20N4/c1-2-6-15(7-3-1)14-22-17-9-5-4-8-16(17)20-18(22)21-12-10-19-11-13-21/h1-9,19H,10-14H2

InChI key: InChIKey=PWWDCRQZITYKDV-UHFFFAOYSA-N

SMILES: N=1C=2C=CC=CC2N(C1N3CCNCC3)CC=4C=CC=CC4

Synonyms:

• 1-(Phenylmethyl)-2-(1-piperazinyl)-1H-benzimidazole
• 1-Benzyl-2-(1-piperazinyl)benzimidazole
• 1-Benzyl-2-(piperazin-1-yl)-1H-1,3-benzodiazole
• 1-benzyl-2-(piperazin-1-yl)-1H-benzimidazole
• 1H-Benzimidazole, 1-(phenylmethyl)-2-(1-piperazinyl)-
• Lerisetron [INN]
• Unii-Q36R82Sxrg
• Lerisetron

Lerisetron

CAS: 143257-98-1

• Formula: C₁₈H₂₀N₄
• Purity: 99%
• Molecular weight: 292.3782

Lerisetron

CAS: 143257-98-1

Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.

• Formula: C₁₈H₂₀N₄
• Purity: 99.15%
• Color and Shape: Solid
• Molecular weight: 292.38

1-Benzyl-2-(piperazin-1-yl)-1H-1,3-benzodiazole

CAS: 143257-98-1

1-Benzyl-2-(piperazin-1-yl)-1H-1,3-benzodiazole is a 5HT agonist that has been shown to stimulate the synthesis of collagen …

• Formula: C₁₈H₂₀N₄
• Purity: Min. 95%
• Molecular weight: 292.4 g/mol

1-benzyl-2-piperazin-1-yl-1H-benzimidazole dihydrochloride

CAS: 143257-98-1

• Purity: 95.0%
• Molecular weight: 365.29998779296875