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CAS 1432610-22-4

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B-(4,5-Difluoro-2-hydroxyphenyl)boronic acid

Description:
B-(4,5-Difluoro-2-hydroxyphenyl)boronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenolic ring that is substituted with two fluorine atoms and a hydroxyl group. This compound typically exhibits properties such as being a white to off-white solid, with solubility in polar solvents like water and alcohols, which is common for boronic acids due to their ability to form hydrogen bonds. The difluorophenyl moiety contributes to its unique electronic properties, potentially enhancing its reactivity in cross-coupling reactions, making it valuable in organic synthesis and medicinal chemistry. Additionally, boronic acids are known for their ability to form reversible complexes with diols, which can be exploited in various applications, including drug delivery and sensor technology. The presence of fluorine atoms can also influence the compound's lipophilicity and biological activity, making it a subject of interest in pharmaceutical research. Overall, B-(4,5-Difluoro-2-hydroxyphenyl)boronic acid is a versatile compound with significant implications in synthetic and medicinal chemistry.
Formula:C6H5BF2O3
InChI:InChI=1S/C6H5BF2O3/c8-4-1-3(7(11)12)6(10)2-5(4)9/h1-2,10-12H
InChI key:InChIKey=YIKIRVLQGNKPFB-UHFFFAOYSA-N
SMILES:B(O)(O)C1=C(O)C=C(F)C(F)=C1
Synonyms:
  • (4,5-Difluoro-2-hydroxyphenyl)boronic acid
  • Boronic acid, B-(4,5-difluoro-2-hydroxyphenyl)-
  • B-(4,5-Difluoro-2-hydroxyphenyl)boronic acid
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