Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that plays a crucial role in immune responses, inflammation, and cell signaling. The precursor form of IL-1β is synthesized as an inactive protein that requires cleavage to become biologically active. The fragment referred to as "interleukin 1B precursor (pil-1B)*(110-123) fragment" likely represents a specific segment of the precursor protein, which may be involved in receptor binding or modulation of immune responses. The CAS number 143305-11-7 identifies this specific fragment, indicating its unique chemical identity. Generally, cytokines like IL-1β are characterized by their ability to induce fever, promote the expression of adhesion molecules, and stimulate the production of other inflammatory mediators. They are typically produced by activated macrophages and other immune cells in response to infection or injury. The study of such fragments can provide insights into their functional roles and potential therapeutic applications in inflammatory diseases and immune regulation.

interleukin 1B precursor (pil-1B)*(110-123) fragm

143305-11-7: Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that plays a crucial role in immune responses, inflammation, and cell signaling. The precursor form of IL-1β is synthesized as an inactive protein that requires cleavage to become biologically active. The fragment referred to as "interleukin 1B precursor (pil-1B)*(110-123) fragment" likely represents a specific segment of the precursor protein, which may be involved in receptor binding or modulation of immune responses. The CAS number 143305-11-7 identifies this specific fragment, indicating its unique chemical identity. Generally, cytokines like IL-1β are characterized by their ability to induce fever, promote the expression of adhesion molecules, and stimulate the production of other inflammatory mediators. They are typically produced by activated macrophages and other immune cells in response to infection or injury. The study of such fragments can provide insights into their functional roles and potential therapeutic applications in inflammatory diseases and immune regulation.

<p>H-Asn-Glu-Ala-Tyr-Val-His-Asp-Ala-Pro-Val-Arg-Ser-Leu-Asn is a cytosolic protein that is an inhibitor of protein synthesis. It has been shown to inhibit the activity of proteases, such as caspase 1, and to activate caspase 1. This inhibition is consequent to the inhibition of polypeptide chain elongation and may be due to the ability of HAAHTVHAAPVVAALAHPVKVALARGSRLEUANNSOH to bind to peptidyl transferase or other proteins involved in protein synthesis. HAAHTVHAAPVVAALAHPVKVALARGSRLEUANNSOH binds to primary keratinocytes and k562 cells more efficiently than it does to thp1 cells, suggesting that it may have a role in skin cancer.</p>

CAS 143305-11-7

interleukin 1B precursor (pil-1B)*(110-123) fragm

H-Asn-Glu-Ala-Tyr-Val-His-Asp-Ala-Pro-Val-Arg-Ser-Leu-Asn-OH

Ref: 3D-FA110895