CAS 143321-89-5
:Acetamide, 2,2,2-trifluoro-N-(2-iodophenyl)-
Description:
Acetamide, 2,2,2-trifluoro-N-(2-iodophenyl)-, is an organic compound characterized by the presence of an acetamide functional group, a trifluoromethyl group, and an iodophenyl substituent. This compound features a carbonyl group (C=O) bonded to a nitrogen atom (N), which is further connected to a phenyl ring substituted with iodine at the ortho position. The trifluoromethyl group, consisting of three fluorine atoms attached to a carbon atom, imparts unique electronic and steric properties, enhancing the compound's reactivity and potential applications in medicinal chemistry. The presence of iodine can also influence the compound's biological activity and solubility. Acetamides generally exhibit moderate polarity, and the trifluoromethyl and iodophenyl groups can significantly affect the compound's overall hydrophobicity and lipophilicity. This compound may be of interest in pharmaceutical research, particularly in the development of new drugs or agrochemicals, due to its potential biological activity and the influence of halogen substituents on molecular interactions.
Formula:C8H5F3INO
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Found 1 products.
2,2,2-Trifluoro-N-(2-iodophenyl)acetamide
CAS:<p>2,2,2-Trifluoro-N-(2-iodophenyl)acetamide is a cross-coupling agent. It can be used as an efficient method for the synthesis of amides and halides by reacting carbinols with halides. 2,2,2-Trifluoro-N-(2-iodophenyl)acetamide has been shown to catalyze the reaction at lower temperatures than other methods. The functional groups on the amide or halide react with the triflate to form a trialkylamine that is then hydrolyzed by water to release ammonia. This reaction is catalysed by base and proceeds via an S1 mechanism. 2,2,2-Trifluoro-N-(2-iodophenyl)acetamide is also used in the production of dioxane and triflates as well as for hydrogenation reactions.</p>Formula:C8H5F3INOPurity:Min. 95%Molecular weight:315.03 g/mol
