CAS 143322-58-1

Eletriptan

Description:

Eletriptan is a selective serotonin receptor agonist primarily used in the treatment of migraine headaches. It belongs to the triptan class of medications, which are designed to alleviate migraine symptoms by targeting serotonin receptors in the brain, specifically the 5-HT_1B and 5-HT_1D subtypes. The chemical formula of eletriptan is C18H21N3O2S, and it features a thiazole ring, which contributes to its pharmacological activity. Eletriptan is known for its rapid onset of action and effectiveness in reducing headache severity and associated symptoms such as nausea and sensitivity to light and sound. It is typically administered orally and is metabolized primarily in the liver, with a half-life that allows for convenient dosing. Common side effects may include dizziness, fatigue, and sensations of tingling or warmth. As with other triptans, it is contraindicated in patients with certain cardiovascular conditions due to the potential for vasoconstriction. Overall, eletriptan is a valuable option in the acute management of migraines.

Formula: C₂₂H₂₆N₂O₂S

InChI: InChI=1S/C22H26N2O2S/c1-24-12-5-6-19(24)15-18-16-23-22-10-9-17(14-21(18)22)11-13-27(25,26)20-7-3-2-4-8-20/h2-4,7-10,14,16,19,23H,5-6,11-13,15H2,1H3/t19-/m1/s1

InChI key: InChIKey=PWVXXGRKLHYWKM-LJQANCHMSA-N

SMILES: C(C=1C=2C(NC1)=CC=C(CCS(=O)(=O)C3=CC=CC=C3)C2)[C@@H]4N(C)CCC4

Synonyms:

• (R)-5-[2-(Benzenesulfonyl)ethyl]-3-[(N-methylpyrrolidin-2-yl)methyl]-1H-indole
• 1H-Indole, 3-[(1-methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethyl]-, (R)-
• 1H-Indole, 3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-
• 3-[(1-Methylpyrrolidin-2-Yl)Methyl]-5-(2-Phenylsulfonylethyl)-1H-Indole
• 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole
• 3-[[(R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]indole
• 3-{[(2R)-1-methylpyrrolidin-2-yl]methyl}-5-[2-(phenylsulfonyl)ethyl]-1H-indole
• 5-(2-(Benzenesulfoyl)vinyl)-3-(1-Methylpyrrolidin-2(R)-ylmethyl)-1H-Indole
• 5-(2-(benzenesulfonyl)vinyl)-3-(1-methylpyrrolidin-2(R)-ylmethyl)-1H-indole
• 5-[2-(benzenesulfonyl)ethyl]-3-[(1-methylpyrrolidin-2-yl)methyl]-1H-indol
• 6-[2-(benzenesulfonyl)ethyl]-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indole hydrobromide
• UK-116044,Relpax,3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole
• Uk 116044

Eletriptan

CAS: 143322-58-1

Eletriptan

Purity: ≥98%

Molecular weight: 382.52g/mol

Ref: 54-BUP22208

Eletriptan

CAS: 143322-58-1

Formula: C₂₂H₂₆N₂O₂S

Molecular weight: 382.52

Ref: 7W-GP0114

Eletriptan

CAS: 143322-58-1

Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.

Formula: C₂₂H₂₆N₂O₂S

Color and Shape: Solid

Molecular weight: 382.52

Ref: TM-T0216L

Eletriptan

CAS: 143322-58-1

Formula: C₂₂H₂₆N₂O₂S

Color and Shape: Yellow To Dark Yellow

Molecular weight: 382.52

Ref: TR-E505000