Lascufloxacin hydrochloride is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, particularly those caused by Gram-negative and some Gram-positive organisms. The compound functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription, thereby disrupting bacterial cell division and growth. Lascufloxacin hydrochloride is typically administered in its hydrochloride salt form, which enhances its solubility and bioavailability. The substance exhibits favorable pharmacokinetic properties, including good tissue penetration and a relatively long half-life, allowing for effective dosing regimens. Additionally, it is important to note that, like other fluoroquinolones, lascufloxacin may be associated with potential side effects, including gastrointestinal disturbances and, in rare cases, tendon damage. As with any antibiotic, appropriate susceptibility testing is recommended to ensure efficacy against specific pathogens and to mitigate the risk of developing antibiotic resistance.

Lascufloxacin hydrochloride

1433857-09-0: Lascufloxacin hydrochloride is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, particularly those caused by Gram-negative and some Gram-positive organisms. The compound functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription, thereby disrupting bacterial cell division and growth. Lascufloxacin hydrochloride is typically administered in its hydrochloride salt form, which enhances its solubility and bioavailability. The substance exhibits favorable pharmacokinetic properties, including good tissue penetration and a relatively long half-life, allowing for effective dosing regimens. Additionally, it is important to note that, like other fluoroquinolones, lascufloxacin may be associated with potential side effects, including gastrointestinal disturbances and, in rare cases, tendon damage. As with any antibiotic, appropriate susceptibility testing is recommended to ensure efficacy against specific pathogens and to mitigate the risk of developing antibiotic resistance.

<p>Lascufloxacin (KRP-AM-1977) is a strong antibiotic, most effective against gram-positive bacteria, with limited cross-resistance.</p>

CAS 1433857-09-0

Lascufloxacin hydrochloride

Lascufloxacin HCl

Ref: TM-T25633