CAS 1434-54-4: Pregnenolone 16α-carbonitrile

Description: Pregnenolone 16α-carbonitrile is a synthetic derivative of pregnenolone, a steroid hormone precursor. It is characterized by the presence of a cyano group (-CN) at the 16α position of the steroid nucleus, which modifies its biological activity. This compound is primarily studied for its role as a selective modulator of steroid hormone receptors, particularly in the context of neurosteroid research. Pregnenolone 16α-carbonitrile exhibits potential neuroprotective effects and may influence various physiological processes, including mood regulation and cognitive function. Its chemical structure contributes to its lipophilicity, allowing it to cross biological membranes effectively. The compound is often utilized in pharmacological studies to explore its effects on the central nervous system and its potential therapeutic applications in conditions such as anxiety and depression. As with many steroid derivatives, its safety profile and pharmacokinetics are important considerations in research and potential clinical use.

Formula: C₂₂H₃₁NO₂

InChI: InChI=1S/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1

InChI key: InChIKey=VSBHRRMYCDQLJF-ZDNYCOCVSA-N

SMILES: N#CC1CC2C3CC=C4CC(O)CCC4(C)C3CCC2(C)C1C(=O)C

Synonyms:

• (3Beta,16Alpha)-3-Hydroxy-20-Oxopregn-5-Ene-16-Carbonitrile
• (3β,16α)-3-Hydroxy-20-oxopregn-5-ene-16-carbonitrile
• 16α-Cyanopregnenolone
• 3beta-Hydroxy-20-oxo-5-pregnene-16alpha-carbonitrile
• 3β-Hydroxy-20-oxo-5-pregnen-16α-carbonitrile
• 3β-Hydroxy-20-oxopregn-5-ene-16α-carbonitrile
• Ccris 9224
• Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3beta,16alpha)-
• Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3β,16α)-
• Pregn-5-ene-16α-carbonitrile, 3β-hydroxy-20-oxo-
• Pregn-5-ene-3β-ol-20-oxo-16α-carbonitrile
• Pregnenolone 16alpha-carbonitrile
• Pregnenolone 16α-carbonitrile
• Pregnenolone carbonitrile
• Sc 4674
• PCN

5-Pregnen-3β-ol-20-one-16α-carbonitrile

CAS: 1434-54-4

• Formula: C₂₂H₃₁NO₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 341.487

5-Pregnen-3β-ol-20-one-16α-carbonitrile

CAS: 1434-54-4

• Formula: C₂₂H₃₁NO₂
• Molecular weight: 341.49

Pregnenolone Carbonitrile

CAS: 1434-54-4

Pregnenolone Carbonitrile (5-Pregnen-3β-ol-20-one-16α-carbonitrile) is an activator of rodent-PXR and induces the expression of CYP3A.

• Formula: C₂₂H₃₁NO₂
• Purity: 99.64%
• Color and Shape: Solid
• Molecular weight: 341.49

Pregnenolone Carbonitrile

CAS: 1434-54-4

Applications Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A …

• Formula: C₂₂H₃₁NO₂
• Color and Shape: Neat
• Molecular weight: 341.49

Pregnenolone-16α-carbonitrile

CAS: 1434-54-4

Please enquire for more information about Pregnenolone-16alpha-carbonitrile including the price, delivery time and more detailed …

• Formula: C₂₂H₃₁NO₂
• Purity: Min. 95%
• Molecular weight: 341.49 g/mol