CAS 143490-53-3

Irinotecan Impurity 2

CAS: 143490-53-3

Formula: C₃₂H₃₆N₄O₅

Molecular weight: 556.67

Ref: 4Z-I-1810

Irinotecan Lactone Impurity

Controlled Product

CAS: 143490-53-3

Applications A lactone impurity of Irinotecan (I767500), a DNA topoisomerase inhibitor. A photodegradation product of a camptothecin derivative used as an anticancer drug.
References Akimoto, K. et al.: J. Chrom. 734, 401 (1996); Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987); Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993); Chen, A., et al.: Annu. Rev. Pharmacol. Toxicol., 34, 191 (1994);

Formula: C₃₂H₃₆N₄O₅

Color and Shape: Neat

Molecular weight: 556.65

Ref: TR-I767520

Irinotecan lactone impurity

CAS: 143490-53-3

Irinotecan is a drug product that is used in the treatment of cancer. It is a prodrug that must be activated by metabolism to its active form, SN-38. Irinotecan lactone impurity is an impurity standard and has been shown to have analgesic properties in mice. It has also been shown to inhibit the growth of colon cancer cells.

Formula: C₃₂H₃₆N₄O₅

Purity: Min. 95%

Molecular weight: 556.7 g/mol

Ref: 3D-II180814