CAS 1435-50-3

2-Bromo-1,4-dichlorobenzene

Description:

2-Bromo-1,4-dichlorobenzene is an aromatic halogenated compound characterized by the presence of two chlorine atoms and one bromine atom attached to a benzene ring. Specifically, the bromine is located at the second position and the chlorine atoms at the first and fourth positions, making it a member of the dichlorobenzene family. This compound is typically a colorless to pale yellow liquid or solid, depending on temperature, and is known for its relatively high melting and boiling points compared to non-halogenated benzene derivatives. It is moderately soluble in organic solvents but has limited solubility in water. 2-Bromo-1,4-dichlorobenzene is used in various applications, including as an intermediate in organic synthesis and in the production of agrochemicals and pharmaceuticals. However, it is important to handle this compound with care due to its potential toxicity and environmental impact, as halogenated compounds can be persistent in the environment and may pose risks to human health.

Formula: C₆H₃BrCl₂

InChI: InChI=1S/C6H3BrCl2/c7-5-3-4(8)1-2-6(5)9/h1-3H

InChI key: InChIKey=OVXVQBCRONSPDC-UHFFFAOYSA-N

SMILES: BrC1=C(Cl)C=CC(Cl)=C1

Synonyms:

• 2,5-Dichlorobromobenzene
• 2-Bromo-1,4-Dichlorobenzene
• Benzene, 1-bromo-2,5-dichloro-
• Benzene, 2-bromo-1,4-dichloro-
• 1-Bromo-2,5-dichlorobenzene

2-Bromo-1,4-dichlorobenzene, 98%

CAS: 1435-50-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₃BrCl₂

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder or clear liquid as melt, Colorless to cream to pale brown

Molecular weight: 225.89

Ref: 02-A12056

Benzene, 2-bromo-1,4-dichloro-

CAS: 1435-50-3

Formula: C₆H₃BrCl₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 225.8980

Ref: IN-DA00HWXN

1-Bromo-2,5-dichlorobenzene

CAS: 1435-50-3

Formula: C₆H₃BrCl₂

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Molecular weight: 225.89

Ref: 3B-B0981

2,5-Dichlorobromobenzene

CAS: 1435-50-3

2,5-Dichlorobromobenzene

Formula: C₆H₃BrCl₂

Purity: ≥95%

Color and Shape: white fused solid

Molecular weight: 225.89802g/mol

Ref: 54-OR1563

1-Bromo-2,5-dichlorobenzene

CAS: 1435-50-3

Formula: C₆H₃BrCl₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 225.89

Ref: 10-F111100

2-Bromo-1,4-dichlorobenzene

Controlled Product

CAS: 1435-50-3

Applications 2-Bromo-1,4-dichlorobenzene is a reactant used in the synthesis of C-13 and C-14-labeled versions of the investigational proteasome inhibitor MLN9708.
References Plesescu, M., et. al.: J. Labelled Compd. Rad., 56, 464 (2013)

Formula: C₆H₃BrCl₂

Color and Shape: Neat

Molecular weight: 225.9

Ref: TR-B683390

1-Bromo-2,5-dichlorobenzene

CAS: 1435-50-3

1-Bromo-2,5-dichlorobenzene is an anticancer drug that belongs to the class of brominated aromatic compounds. The vibrational spectra of 1-bromo-2,5-dichlorobenzene have been characterized by FTIR. The anticancer activity of 1-bromo-2,5-dichlorobenzene has been shown in in vitro and in vivo studies. It is orally active and has a low toxicity profile. The major metabolite of 1-Bromo-2,5-dichlorobenzene is 2,6 dichloropyridine, which can be detected by mass spectrometry. The metabolites are thought to be formed by dehydration or Friedel–Crafts acylation reactions.

Formula: C₆H₃BrCl₂

Purity: Min. 95%

Molecular weight: 225.89 g/mol

Ref: 3D-BAA43550