CAS 1435784-14-7

Lometrexol hydrate

CAS: 1435784-14-7

Lometrexol hydrate is an inhibitor of the enzyme thymidylate synthase, which is involved in DNA synthesis. This drug has been shown to be effective against a variety of tumors, including those that produce high levels of hyaluronan or testosterone. Lometrexol hydrate has also been shown to inhibit the growth of cancer cells by blocking the activity of certain kinases, leading to apoptosis (cell death). In human studies, lometrexol hydrate has been found to be effective in treating various types of cancer, including lung and ovarian cancer. This drug is available as an analog and can be detected in urine samples. Lometrexol hydrate has also been studied in Chinese medicine for its potential use in combination with octreotide for the treatment of certain cancers.

Formula: C₂₁H₂₇N₅O₇

Purity: Min. 95%

Molecular weight: 461.5 g/mol

Ref: 3D-KHC78414

Lometrexol hydrate

CAS: 1435784-14-7

Lometrexol hydrate, an antipurine antifolate, inhibits GARFT and purine synthesis, leading to cancer cell apoptosis without causing DNA breaks.

Formula: C₂₁H₂₇N₅O₇

Color and Shape: Solid

Molecular weight: 461.475

Ref: TM-T41297