CAS 143584-75-2

S-methyl-KE-298

Description:

S-methyl-KE-298, with the CAS number 143584-75-2, is a chemical compound that belongs to the class of sulfonamides. It is characterized by the presence of a methyl group attached to a sulfur atom, which is part of a sulfonamide functional group. This compound is often studied for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its biological activity. S-methyl-KE-298 may exhibit properties such as solubility in organic solvents and varying stability under different pH conditions. Its molecular structure typically includes a sulfonyl group, which can influence its reactivity and interaction with biological targets. Additionally, the compound may undergo various chemical reactions, including nucleophilic substitutions and hydrolysis, depending on the surrounding environment. As with many sulfonamides, it may also possess antibacterial properties, making it of interest in the field of drug development. However, specific characteristics such as melting point, boiling point, and spectral data would require further investigation or reference to specialized databases.

Formula: C₁₃H₁₆O₃S

Synonyms:

• S-methyl-KE-298
• -KE-298

S-methyl-KE-298

CAS: 143584-75-2

Formula: C₁₃H₁₆O₃S

Purity: 95%

Molecular weight: 252.3293

Ref: IN-DA01EOFB

S-methyl-KE-298

CAS: 143584-75-2

S-methyl-KE-298

Purity: ≥95%

Molecular weight: 252.33g/mol

Ref: 54-BUP05571

S-methyl-KE-298

CAS: 143584-75-2

S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production

Formula: C₁₃H₁₆O₃S

Purity: 97.33%

Color and Shape: Solid

Molecular weight: 252.33

Ref: TM-T4282

S-Methyl-ke-298

CAS: 143584-75-2

S-Methyl-ke-298 is a new chiral, antirheumatic drug that is administered orally. It has been shown to be well tolerated in human clinical trials and to have pharmacokinetic properties that are stereoselectively different from the racemic drug. Pharmacokinetic studies in rats demonstrated that S-methyl-ke-298 had high plasma protein binding (95%) and was rapidly eliminated from plasma with a half-life of approximately 2 hours. The elimination of S-methyl-ke-298 was more rapid than the elimination of its enantiomer, R-(+)-methyl ke 298. This difference may be due to the fact that S-methyl ke 298 is more lipophilic than R-(+)-methyl ke 298 and therefore crosses the blood brain barrier more easily.
S-[(R)-1-(3,4,5 -trimethoxyphenyl) ethyl] methyl ketone (SEMK) is an enantiomer

Formula: C₁₃H₁₆O₃S

Purity: Min. 95%

Molecular weight: 252.33 g/mol

Ref: 3D-TFA58475