CAS 143756-46-1

2-(4'-(IODOACETAMIDO)ANILINO)NAPHTHALENE-6-SULFONIC ACID SODIUM SALT

Description:

2-(4'-(Iodoacetamido)anilino)naphthalene-6-sulfonic acid sodium salt is a chemical compound characterized by its complex structure, which includes a naphthalene ring substituted with a sulfonic acid group and an aniline derivative containing an iodoacetamido group. This compound is typically used in biochemical applications, particularly in the field of fluorescence labeling and as a reagent in various chemical assays due to its fluorescent properties. The presence of the sulfonic acid group enhances its solubility in aqueous solutions, making it suitable for biological studies. Additionally, the iodoacetamido group allows for covalent bonding to biomolecules, facilitating the study of protein interactions and dynamics. The sodium salt form indicates that the sulfonic acid is neutralized with sodium, which further increases its stability and solubility. Overall, this compound is valuable in research settings, particularly in the development of fluorescent probes and in the study of molecular interactions in biological systems.

Formula: C₁₈H₁₄IN₂NaO₄S

InChI: InChI=1/C18H15IN2O4S.Na/c19-11-18(22)21-15-6-4-14(5-7-15)20-16-3-1-13-10-17(26(23,24)25)8-2-12(13)9-16;/h1-10,20H,11H2,(H,21,22)(H,23,24,25);/q;+1/p-1

SMILES: c1cc(cc2ccc(cc12)S(=O)(=O)O)Nc1ccc(cc1)NC(=O)CI.[Na]

Synonyms:

• Iaans
• Iaans, Sodium Salt
• Sodium 6-({4-[(Iodoacetyl)Amino]Phenyl}Amino)Naphthalene-2-Sulfonate

IAANS (>80%)

CAS: 143756-46-1

Formula: C₁₈H₁₄IN₂O₄S·Na

Purity: >80%

Color and Shape: Light Green To Dark Green

Molecular weight: 504.27

Ref: TR-I100005

IAANS-d4

CAS: 143756-46-1

IAANS-d4 is an inhibitor that has been shown to induce apoptosis in cancer cells. It is an analog of IAANS, a potent anticancer agent that was originally isolated from urine. IAANS-d4 has been found to inhibit the activity of various kinases, including protein kinase C and MAP kinase. This inhibition leads to decreased cell proliferation and increased apoptosis in human tumor cells. Additionally, IAANS-d4 has shown promising results as a potential medicinal agent for the treatment of cancer due to its ability to inhibit tumor growth in Chinese hamsters. With its potent activity against kinases and ability to induce apoptosis, IAANS-d4 holds great potential as a new class of anticancer agents.

Formula: C₁₈H₁₄IN₂NaO₄S

Purity: Min. 95%

Molecular weight: 504.3 g/mol

Ref: 3D-TFA75646