CAS 143782-25-6

2-(Trifluoromethyl)-4-(3,4,4-trimethyl-5-oxo-2-thioxo-1-imidazolidinyl)benzonitrile

Description:

2-(Trifluoromethyl)-4-(3,4,4-trimethyl-5-oxo-2-thioxo-1-imidazolidinyl)benzonitrile, with the CAS number 143782-25-6, is a synthetic organic compound characterized by its complex molecular structure, which includes a trifluoromethyl group and an imidazolidinyl moiety. This compound typically exhibits properties associated with both aromatic and heterocyclic chemistry, contributing to its potential applications in pharmaceuticals and agrochemicals. The presence of the trifluoromethyl group often enhances lipophilicity and metabolic stability, while the imidazolidinyl structure may impart biological activity. The compound is likely to be solid at room temperature and may exhibit moderate solubility in organic solvents. Its reactivity can be influenced by the electron-withdrawing nature of the trifluoromethyl group and the functional groups present in the imidazolidinyl ring. Overall, this compound's unique characteristics make it a subject of interest for further research in medicinal chemistry and material science.

Formula: C₁₄H₁₂F₃N₃OS

InChI: InChI=1S/C14H12F3N3OS/c1-13(2)11(21)20(12(22)19(13)3)9-5-4-8(7-18)10(6-9)14(15,16)17/h4-6H,1-3H3

InChI key: InChIKey=HLBUAKQNKJTEIU-UHFFFAOYSA-N

SMILES: S=C1N(C(=O)C(C)(C)N1C)C2=CC(C(F)(F)F)=C(C#N)C=C2

Synonyms:

• 2-(Trifluoromethyl)-4-(3,4,4-trimethyl-5-oxo-2-thioxo-1-imidazolidinyl)benzonitrile
• 4-(5-Oxo-2-thioxo-3,4,4-trimethyl-1-imidazolidinyl)-2-trifluoromethylbenzonitrile
• Benzonitrile, 2-(Trifluoromethyl)-4-(3,4,4-Trimethyl-5-Oxo-2-Thioxo-1-Imidazolidinyl)-
• Ru 56187

4-(5-Oxo-2-thioxo-3,4,4-trimethyl-1-imidazolidinyl)-2-trifluoromethylbenzonitrile

Controlled Product

CAS: 143782-25-6

Applications 4-(5-Oxo-2-thioxo-3,4,4-trimethyl-1-imidazolidinyl)-2-trifluoromethylbenzonitrile is a steroid hormone that regulates prostate-specific antigen gene expression in breast cancer.
References Zarghami, N. et al., Br. J. Cancer. 75,579-588(1997);

Formula: C₁₄H₁₂F₃N₃OS

Color and Shape: Neat

Molecular weight: 327.325

Ref: TR-O356845

RU-56187

CAS: 143782-25-6

RU-56187 is an antagonist of progestins, estrogens and androgens, it down-regulates KLK10 expression.

Formula: C₁₄H₁₂F₃N₃OS

Color and Shape: Solid

Molecular weight: 327.32

Ref: TM-T28625