CymitQuimica logo

CAS 1438-30-8

:

Netropsin

Description:
Netropsin is a naturally occurring antibiotic and a member of the class of compounds known as minor groove binders. It is derived from the bacterium *Streptomyces netropsis*. The chemical structure of netropsin features a polyamine backbone that allows it to interact specifically with the minor groove of DNA, thereby influencing gene expression and exhibiting potential antitumor properties. Its mechanism of action involves binding to specific sequences of DNA, which can inhibit the transcription of certain genes. Netropsin has been studied for its potential therapeutic applications, particularly in cancer treatment and as an antiviral agent. The compound is characterized by its relatively low solubility in water, which can affect its bioavailability. Additionally, netropsin has shown a range of biological activities, including antibacterial and antiviral effects, making it a subject of interest in medicinal chemistry. However, its clinical use is limited due to toxicity and side effects, prompting ongoing research into safer analogs and derivatives.
Formula:C18H26N10O3
InChI:InChI=1S/C18H26N10O3/c1-27-9-11(6-12(27)16(30)23-4-3-14(19)20)26-17(31)13-5-10(8-28(13)2)25-15(29)7-24-18(21)22/h5-6,8-9H,3-4,7H2,1-2H3,(H3,19,20)(H,23,30)(H,25,29)(H,26,31)(H4,21,22,24)
InChI key:InChIKey=IDBIFFKSXLYUOT-UHFFFAOYSA-N
SMILES:C(NC=1C=C(C(NCCC(=N)N)=O)N(C)C1)(=O)C2=CC(NC(CNC(=N)N)=O)=CN2C
Synonyms:
  • 1H-Pyrrole-2-carboxamide, 4-[[2-[(aminoiminomethyl)amino]acetyl]amino]-N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-
  • 1H-Pyrrole-2-carboxamide, 4-[[[(aminoiminomethyl)amino]acetyl]amino]-N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-
  • 1’-Dimethyl-L)Amino)-
  • 2814-A
  • 4-[[2-[(Aminoiminomethyl)amino]acetyl]amino]-N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-1H-pyrrole-2-carboxamide
  • Antibiotic1142
  • Antibiotict-1384
  • Ch-777-A
  • Congocidin
  • Congocidine
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
  • Netropsin
    Targetmol
    + Info

    Netropsin

    CAS:
    <p>Netropsin: polypeptide from Streptomyces, with antibiotic/antiviral properties, binds to A-T DNA regions, effective on Gram-positive/negative bacteria.</p>
    Formula:C18H26N10O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.46

    Ref: TM-T21475

  • Netropsin dihydrochloride
    Glentham
    + Info

    Netropsin dihydrochloride

    CAS:
    Formula:C18H26N10O3·2HCl
    Purity:≥ 98.0%
    Color and Shape:Light yellow to yellow powder
    Molecular weight:503.39

    Ref: 7W-GA6301

    ne
    To inquire