CAS 143851-98-3

N-{4-[2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl]phenyl}-5-methoxy-9-oxo-9,10-dihydroacridine-4-carboxamide hydrochloride (1:1)

Description:

N-{4-[2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl]phenyl}-5-methoxy-9-oxo-9,10-dihydroacridine-4-carboxamide hydrochloride is a complex organic compound characterized by its multi-ring structure, which includes an acridine moiety and an isoquinoline derivative. This compound features various functional groups, such as methoxy and carboxamide, contributing to its potential biological activity. The presence of the hydrochloride salt form indicates enhanced solubility in aqueous environments, which is often beneficial for pharmacological applications. The compound's intricate structure suggests potential interactions with biological targets, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its specific properties, such as solubility, stability, and reactivity, would depend on the molecular interactions and the environment in which it is studied. Overall, this substance exemplifies the complexity and diversity of organic compounds used in research and drug development.

Formula: C₃₄H₃₄ClN₃O₅

InChI: InChI=1/C34H33N3O5.ClH/c1-40-28-9-5-7-26-32(28)36-31-25(33(26)38)6-4-8-27(31)34(39)35-24-12-10-21(11-13-24)14-16-37-17-15-22-18-29(41-2)30(42-3)19-23(22)20-37;/h4-13,18-19H,14-17,20H2,1-3H3,(H,35,39)(H,36,38);1H

SMILES: COc1cccc2c1[nH]c1c(cccc1C(=O)Nc1ccc(cc1)CCN1CCc3cc(c(cc3C1)OC)OC)c2=O.Cl

Synonyms:

• 4'-(2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl)-5-methoxy-9-oxo-4-acridancarboxanilide Monohydrochloride
• Gf 120918A
• N-(4-(2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl)phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide Hydrochloride
• N-(4-(2-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-5-methoxy-9-oxo-9,10-dihydroacridine-4-carboxamide Hydrochloride

4-Acridinecarboxamide, N-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-, hydrochloride (1:1)

CAS: 143851-98-3

Formula: C₃₄H₃₄ClN₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 600.1039

Ref: IN-DA001IHB

Elacridar Hydrochloride

Controlled Product

CAS: 143851-98-3

Applications Elacridar Hydrochloride is a dual P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor.
References Chuan Tang, S., et al.: Int. J. Cancer, 134, 1484 (2014); Durmus, S., et al.: Mol. Pharm., 9, 3236 (2012)

Formula: C₃₄H₃₃N₃O₅•xHCl

Color and Shape: Neat

Molecular weight: 563.64

Ref: TR-E489005

Elacridar hydrochloride

CAS: 143851-98-3

Inhibitor of ABC transporters; oral bioenhancer for anti-cancer therapy

Formula: C₃₄H₃₄ClN₃O₅

Purity: Min. 98 Area-%

Color and Shape: Yellow Powder

Molecular weight: 600.11 g/mol

Ref: 3D-FE65016