CAS 14389-06-1

5-Chloro-7-methylisatin

Description:

5-Chloro-7-methylisatin is an organic compound belonging to the isatin family, characterized by its fused aromatic and carbonyl structures. It features a chloro substituent at the 5-position and a methyl group at the 7-position of the isatin core, which contributes to its unique chemical properties. This compound is typically a solid at room temperature and exhibits a pale yellow to brownish color. It is known for its potential biological activities, including antimicrobial and anticancer properties, making it of interest in medicinal chemistry. The presence of the chloro group enhances its reactivity, allowing for various chemical modifications. Additionally, 5-Chloro-7-methylisatin can participate in various reactions, such as nucleophilic substitutions and cyclizations, which are valuable in synthetic organic chemistry. Its solubility varies depending on the solvent, and it is generally more soluble in polar organic solvents. As with many isatin derivatives, it may also exhibit fluorescence under certain conditions, which can be useful for analytical applications.

Formula: C₉H₆ClNO₂

InChI: InChI=1/C9H6ClNO2/c1-4-2-5(10)3-6-7(4)11-9(13)8(6)12/h2-3H,1H3,(H,11,12,13)

SMILES: Cc1cc(cc2c1NC(=O)C2=O)Cl

Synonyms:

• 5-chloro-7-methyl-1H-indole-2,3-dione

5-Chloro-7-methylisatin, 97%

CAS: 14389-06-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₆ClNO₂

Purity: 97%

Color and Shape: Powder, Orange to red to brown

Molecular weight: 195.60

Ref: 02-L11682

1H-Indole-2,3-dione, 5-chloro-7-methyl-

CAS: 14389-06-1

Formula: C₉H₆ClNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 195.6024

Ref: IN-DA001ILB

5-chloro-7-methylindoline-2,3-dione

CAS: 14389-06-1

5-chloro-7-methylindoline-2,3-dione

Purity: 95%

Molecular weight: 195.60244g/mol

Ref: 54-OR28542

5-Chloro-7-methylisatin

CAS: 14389-06-1

Formula: C₉H₆ClNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 195.6

Ref: 10-F047097

5-Chloro-7-methylisatin

CAS: 14389-06-1

5-Chloro-7-methylisatin is an azomethine heterocycle, a class of compounds with a nitrogen atom in the ring. It has been shown to inhibit the growth of staphylococcus by acting as a competitive inhibitor of DNA gyrase and topoisomerase IV. 5-Chloro-7-methylisatin also shows minimal inhibitory concentrations against bacterial strains that are resistant to other antibiotics, such as penicillin and erythromycin. This compound binds to the active site of DNA gyrase and topoisomerase IV, preventing them from binding to DNA or interacting with other enzymes. The chlorine atoms in this molecule may act as electron withdrawing groups and provide some degree of regioselectivity. 5-Chloro-7-methylisatin can exist in two isomers: cis (Z) and trans (E). The cis form is shown to have better antibacterial activity than the trans form

Formula: C₉H₆ClNO₂

Purity: Min. 90%

Color and Shape: Powder

Molecular weight: 195.6 g/mol

Ref: 3D-FC04112