CAS 1439399-58-2

CB-839

Description:

CB-839, with the CAS number 1439399-58-2, is a small molecule inhibitor that specifically targets the enzyme glutaminase. This compound is of particular interest in cancer research due to its potential to disrupt the metabolic pathways that cancer cells rely on for growth and proliferation. By inhibiting glutaminase, CB-839 aims to reduce the availability of glutamine, an amino acid that many tumors utilize to support their energy needs and biosynthetic processes. The substance has been studied in various preclinical and clinical settings, particularly in relation to solid tumors and hematological malignancies. CB-839 is typically characterized by its moderate solubility in organic solvents and its stability under physiological conditions. Its mechanism of action highlights the importance of metabolic reprogramming in cancer therapy, making it a promising candidate for combination therapies aimed at enhancing the efficacy of existing treatments. As research continues, the full therapeutic potential and safety profile of CB-839 are being evaluated in clinical trials.

2-Pyridineacetamide, N-[5-[4-[6-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-3-pyridazinyl]butyl]-1,3,4-thiadiazol-2-yl]-

CAS: 1439399-58-2

Formula: C₂₆H₂₄F₃N₇O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 571.5741

Ref: IN-DA001IMQ

Telaglenastat

CAS: 1439399-58-2

Telaglenastat

Purity: ≥95%

Molecular weight: 571.57g/mol

Ref: 54-BUP11908

Telaglenastat

CAS: 1439399-58-2

Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.

Formula: C₂₆H₂₄F₃N₇O₃S

Purity: 97.57% - 99.89%

Color and Shape: Solid

Molecular weight: 571.57

Ref: TM-T6797

CB-839

Controlled Product

CAS: 1439399-58-2

Formula: C₂₆H₂₄F₃N₇O₃S

Color and Shape: Neat

Molecular weight: 571.57

Ref: TR-C227095

CB 839

CAS: 1439399-58-2

Inhibitor of glutaminase; anti-proliferative

Formula: C₂₆H₂₄F₃N₇O₃S

Purity: Min. 95%

Molecular weight: 571.58 g/mol

Ref: 3D-FC103571