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CAS 144-11-6

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(±)-Trihexyphenidyl

Description:
(±)-Trihexyphenidyl is a synthetic anticholinergic medication primarily used to treat Parkinson's disease and drug-induced extrapyramidal symptoms. It functions by blocking the action of acetylcholine at muscarinic receptors, which helps to alleviate symptoms such as tremors and rigidity. The compound is characterized by its chemical structure, which includes a phenyl ring and a piperidine moiety, contributing to its pharmacological activity. It is typically administered orally and has a relatively long half-life, allowing for once or twice daily dosing. The substance is known for its potential side effects, which may include dry mouth, blurred vision, constipation, and urinary retention, due to its anticholinergic properties. Additionally, (±)-Trihexyphenidyl is classified as a controlled substance in some jurisdictions due to its potential for misuse and side effects. Its efficacy and safety profile make it a valuable option in the management of movement disorders, although careful monitoring is essential to mitigate adverse effects.
Formula:C20H31NO
InChI:InChI=1S/C20H31NO/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2
InChI key:InChIKey=HWHLPVGTWGOCJO-UHFFFAOYSA-N
SMILES:C(CCN1CCCCC1)(O)(C2CCCCC2)C3=CC=CC=C3
Synonyms:
  • (.+-.)-Triphenidyl
  • 1-Cyclohexyl-1-Phenyl-3-(1-Piperidyl)Propan-1-Ol
  • 1-Cyclohexyl-1-Phenyl-3-(Piperidin-1-Yl)Propan-1-Ol
  • 1-Cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol
  • 1-Piperidinepropanol, α-cyclohexyl-α-phenyl-
  • Benzhexol
  • Nsc 12268
  • Trihexifenidilo
  • Trihexyphenidyl
  • Trihexyphenidyle
  • α-Cyclohexyl-α-phenyl-1-piperidinepropanol
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