CAS 144-14-9

Anileridine

Description:

Anileridine is a synthetic opioid analgesic that is primarily used for its pain-relieving properties. It is classified as a piperidine derivative and is known for its ability to provide moderate to severe pain relief. The substance has a chemical formula that reflects its complex structure, which includes a phenyl group and a piperidine ring. Anileridine acts on the central nervous system by binding to opioid receptors, leading to effects such as analgesia, sedation, and euphoria. However, it also carries a risk of side effects, including respiratory depression, constipation, and potential for dependence or abuse. Due to these risks, its clinical use has diminished over time, and it is less commonly prescribed compared to other opioids. Anileridine is typically administered via injection and is subject to strict regulatory controls in many countries. Its pharmacokinetics involve metabolism primarily in the liver, with excretion occurring through the kidneys. Overall, while effective for pain management, careful consideration of its risks and benefits is essential in clinical practice.

Formula: C₂₂H₂₈N₂O₂

InChI: InChI=1S/C22H28N2O2/c1-2-26-21(25)22(19-6-4-3-5-7-19)13-16-24(17-14-22)15-12-18-8-10-20(23)11-9-18/h3-11H,2,12-17,23H2,1H3

InChI key: InChIKey=LKYQLAWMNBFNJT-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C1(CCN(CCC2=CC=C(N)C=C2)CC1)C3=CC=CC=C3

Synonyms:

• 1-(p-Aminophenethyl)-4-phenylpiperidine-4-carboxylic acid ethyl ester
• Adopol
• Alidine
• Anileridine
• Apidol
• Ethyl 1-(4-aminophenethyl)-4-phenylisonipecotate
• Ethyl 1-(p-aminophenethyl)-4-phenylisonipecotate
• Isonipecotic acid, 1-(p-aminophenethyl)-4-phenyl-, ethyl ester
• Leritin
• Leritine
• Nipecotan
• ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate
• 4-Piperidinecarboxylic acid, 1-[2-(4-aminophenyl)ethyl]-4-phenyl-, ethyl ester

Anileridine

Controlled Product

CAS: 144-14-9

Applications A synthetic analgesic drug. 4-phenylpiperidine derivative that is an analog of Meperidine (M223900) with increased analgesic activity.
References Freeman, D.S. et al.: J. Pharamcol. Exp. Therap., 203, 203 (1977); Abbit, F.V.: Phamacol. Biochem. Behav., 24, 1247 (1986);

Formula: C₂₂H₂₈N₂O₂

Color and Shape: Neat

Molecular weight: 352.47

Ref: TR-A660750

Anileridine (1 mg/mL in ethyl acetate)

Controlled Product

CAS: 144-14-9

Formula: C₂₂H₂₈N₂O₂

Color and Shape: Single Solution

Molecular weight: 352.47

Ref: TR-KIT8505