CAS 144-48-9
:Iodoacetamide
Description:
Iodoacetamide is an organic compound with the molecular formula C2H4INO. It is classified as an alkylating agent, primarily used in biochemical research and protein chemistry. This compound features an iodo group attached to an acetamide moiety, making it a potent reagent for modifying proteins and peptides, particularly through the alkylation of cysteine residues. Iodoacetamide is typically a white to off-white solid that is soluble in water and organic solvents, such as ethanol and dimethyl sulfoxide (DMSO). It is known for its ability to form stable adducts with thiol groups, which is crucial in studies involving protein structure and function. Due to its reactivity, it must be handled with care, as it can be toxic and irritating to skin and mucous membranes. In laboratory settings, it is often used in the preparation of samples for mass spectrometry and in the study of enzyme mechanisms. Proper safety protocols should be followed when working with this compound to mitigate any health risks.
Formula:C2H4INO
InChI:InChI=1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
InChI key:InChIKey=PGLTVOMIXTUURA-UHFFFAOYSA-N
SMILES:C(CI)(N)=O
Synonyms:- 2-Iodacetamid
- 2-Iodoacetamida
- 2-Iodoacetamide
- Acetamide, Iodo
- Deltop
- Iodoacetamide
- Monoiodoacetamide
- Nsc 9581
- Surauto
- α-Iodoacetamide
- Acetamide, 2-iodo-
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 12 products.
2-Iodoacetamide [for Biochemical Research]
CAS:Formula:C2H4INOPurity:>98.0%(N)Color and Shape:White to Light yellow powder to crystalMolecular weight:184.96Iodoacetamide
CAS:Formula:C2H4INOPurity:97%Color and Shape:Light yellow crystallineMolecular weight:184.9642-Iodoacetamide, 98%, stab. with ca 5-8% water
CAS:<p>Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind</p>Formula:C2H4INOPurity:5-8%Color and Shape:White to cream to yellow to pale brown, Crystals or powder or crystalline powderMolecular weight:184.96Iodoacetamide
CAS:Formula:ICH2CONH2Purity:≥ 98.0%Color and Shape:White to off-white or pale yellow crystalline powderMolecular weight:184.962-Iodoacetamide
CAS:<p>2-Iodoacetamide</p>Formula:C2H4INOPurity:98%Color and Shape: white to off-white crystalline powderMolecular weight:184.96g/mol2-Iodoacetamide
CAS:<p>Iodoacetamide, an alkylating agent, is commonly utilized for cysteine alkylation in proteomics sample preparation.</p>Formula:C2H4INOPurity:98.54% - 99.95%Color and Shape:CrystallineMolecular weight:184.962-Iodoacetamide
CAS:<p>Applications 2-Iodoacetamide is an alkylating agent commonly used in the alkylation of proteins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Woods, A.G.,et. al.: Biochem. Bioph. Res. Co., 419, 305 (2012); Samgina, T.Y., et. al.: J. Am. Soc. Mass Spec., 22, 2246 (2011)<br></p>Formula:C2H4INOColor and Shape:NeatMolecular weight:184.962-Iodoacetamide
CAS:<p>2-Iodoacetamide is a synthetic retinoid that binds to the DNA of cells, altering transcription. It also has been found to be effective in treating bowel disease and has been shown to have dna binding activity. The compound was synthesized by attaching iodine molecules to acetamide. 2-Iodoacetamide targets the protein thiols on the surface of cells, which are responsible for oxidation and damage due to reactive oxygen species (ROS). This compound is metabolized by alcohol dehydrogenase and can be used as a biological sample or natural compound.</p>Formula:C2H4INOPurity:Min. 95%Color and Shape:SolidMolecular weight:184.96 g/mol
![2-Iodoacetamide [for Biochemical Research]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FI0741.jpg&w=3840&q=75)
