CAS 144-74-1

Sodium sulfathiazole

Description:

Sodium sulfathiazole, with the CAS number 144-74-1, is a sulfonamide antibiotic that exhibits antimicrobial properties. It is a sodium salt of sulfathiazole, which is a derivative of sulfanilamide. This compound is typically characterized by its white to off-white crystalline appearance and is soluble in water, making it suitable for various pharmaceutical formulations. Sodium sulfathiazole functions by inhibiting bacterial growth through the competitive inhibition of the enzyme dihydropteroate synthase, which is crucial in the synthesis of folate in bacteria. It is primarily used in veterinary medicine and has applications in treating infections in livestock. While it has been effective against a range of bacterial infections, its use has declined due to the development of antibiotic resistance and the availability of more effective alternatives. Safety considerations include potential allergic reactions and the need for careful dosage to avoid toxicity. Overall, sodium sulfathiazole remains an important compound in the study of antimicrobial agents and their mechanisms of action.

Formula: C₉H₉N₃O₂S₂·Na

InChI: InChI=1S/C9H9N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-6H,10H2,(H,11,12);

InChI key: InChIKey=RKXDGQFOLMYFFG-UHFFFAOYSA-N

SMILES: S(NC1=NC=CS1)(=O)(=O)C2=CC=C(N)C=C2.[Na]

Synonyms:

• 2-(p-Amino-N-sodiobenzenesulfonamide)thiazole
• 2-(p-Aminobenzenesulfonamido)thiazole sodium salt
• 2-Sulfanilamidothiazole sodium salt
• 4-Amino-N-(2-thiazolyl)benzenesulfonamide sodium salt
• Benzenesulfonamide, 4-amino-N-2-thiazolyl-, monosodium salt
• Benzenesulfonamide, 4-amino-N-2-thiazolyl-, sodium salt (1:1)
• Norsulfazol sodium
• Norsulfazole sodium
• Norsulfazole sodium salt
• Norsulfazole soluble
• ST-Na
• Sodium 2-sulfanilamidothiazole
• Sodium [(4-Aminophenyl)Sulfonyl](1,3-Thiazol-2-Yl)Azanide
• Sodium norsulfazole
• Sodium sulfathiazolate
• Sodium sulfathiazole
• Sodium, (N¹-2-thiazolylsulfanilamido)-
• Soluble norsulfazole
• Soluble sulfathiazole
• Soluthiazomide
• Sulfanilamide, N¹-2-thiazolyl-, monosodium salt
• Sulfathiazole sodium salt
• Sulfathiazole, sodium deriv.
• Sulphathiazole sodium
• Sodium, (N1-2-thiazolylsulfanilamido)-

Sulfathiazole (sodium)

CAS: 144-74-1

Formula: C₉H₈N₃NaO₂S₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 277.2985

Ref: IN-DA007Z08

Sulfathiazole sodium salt

CAS: 144-74-1

Formula: C₉H₈N₃NaO₂S₂

Purity: 99.0 - 101.0 % (anhydrous basis)

Color and Shape: White, off-white or pale yellow powder

Molecular weight: 277.30

Ref: 7W-GA2698

Sodium ((4-Aminophenyl)Sulfonyl)(Thiazol-2-Yl)Amide

CAS: 144-74-1

Sodium ((4-Aminophenyl)Sulfonyl)(Thiazol-2-Yl)Amide

Purity: 99%

Molecular weight: 277.30g/mol

Ref: 54-OR1014931

Sulfathiazole Sodium Salt

CAS: 144-74-1

Formula: C₉H₈N₃O₂S₂·Na

Color and Shape: White To Off-White Solid

Molecular weight: 254.31 22.99

Ref: 4Z-S-111002

Sulfathiazole sodium

CAS: 144-74-1

Sulfathiazole Sodium is an organosulfur compound. It also has been used as a short-acting sulfa drug.

Formula: C₉H₉N₃NaO₂S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 278.31

Ref: TM-T23402

Sulfathiazole Sodium Salt

CAS: 144-74-1

Formula: C₉H₈N₃O₂S₂·Na

Color and Shape: Neat

Molecular weight: 277.298

Ref: TR-S699108

Sulfathiazole sodium

CAS: 144-74-1

Sulfathiazole sodium is a sulfonamide antibiotic that has been used to treat a variety of infections caused by bacteria and protozoa. It is also used as an adjunct in the treatment of some types of pneumonia. Sulfathiazole sodium is chemically stable in aqueous solution, but the chemical stability decreases with increasing concentration of potassium ions and increasing pH. Sulfathiazole sodium may cause depression and inhibit atropine sulfate-induced pupil dilation when administered together. The drug may cause hyperactivity, but this effect is not seen in all patients. Sulfathiazole sodium has been shown to have immunostimulatory effects on h295r cells, which are cells from human renal carcinoma, through the activation of oxidative stress pathways.

Formula: C₉H₈N₃NaO₂S₂

Purity: Min. 95%

Color and Shape: Off-White To Yellow Solid

Molecular weight: 277.3 g/mol

Ref: 3D-FS40868