CAS 144025-03-6

2,4-Difluorophenylboronic acid

Description:

2,4-Difluorophenylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenyl ring that has two fluorine substituents at the 2 and 4 positions. This compound typically appears as a white to off-white solid and is soluble in polar solvents such as water and alcohols, owing to the boronic acid group, which can form hydrogen bonds. The presence of fluorine atoms enhances its electronic properties, making it useful in various applications, including medicinal chemistry and materials science. It can participate in Suzuki-Miyaura cross-coupling reactions, which are pivotal in the synthesis of biaryl compounds. Additionally, 2,4-difluorophenylboronic acid can act as a ligand in coordination chemistry and is of interest in the development of sensors and drug delivery systems due to its ability to interact with biological molecules. Safety precautions should be taken when handling this compound, as with many organoboron compounds, due to potential toxicity and reactivity.

Formula: C₆H₅BF₂O₂

InChI: InChI=1S/C6H5BF2O2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,10-11H

InChI key: InChIKey=QQLRSCZSKQTFGY-UHFFFAOYSA-N

SMILES: B(O)(O)C1=C(F)C=C(F)C=C1

Synonyms:

• 2,4-Difluorophenyl-1-boronic acid
• 2,4-Difluorophenyl-Boronic Acid
• 2,4-Difluorophenylboronic acid
• B-(2,4-Difluorophenyl)boronic acid
• Boronic acid, (2,4-difluorophenyl)-
• Boronic acid, B-(2,4-difluorophenyl)-
• 2,4-Difluorobenzeneboronic acid

2,4-Difluorophenylboronic Acid (contains varying amounts of Anhydride)

CAS: 144025-03-6

Formula: C₆H₅BF₂O₂

Color and Shape: White to Almost white powder to crystal

Molecular weight: 157.91

Ref: 3B-D3391

2,4-Difluorobenzeneboronic acid, 97%

CAS: 144025-03-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₅BF₂O₂

Purity: 97%

Color and Shape: White to pale yellow, Crystals or powder or crystalline powder

Molecular weight: 157.91

Ref: 02-B23821

Boronic acid, B-(2,4-difluorophenyl)-

CAS: 144025-03-6

Formula: C₆H₅BF₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 157.9105

Ref: IN-DA001ISZ

2,4-Difluorobenzeneboronic acid

CAS: 144025-03-6

2,4-Difluorobenzeneboronic acid

Formula: C₆H₅BF₂O₂

Purity: ≥95%

Color and Shape: white solid

Molecular weight: 157.91g/mol

Ref: 54-PC9097

2,4-Difluorophenylboronic acid

CAS: 144025-03-6

Formula: C₆H₅BF₂O₂

Molecular weight: 157.91

Ref: 7W-GK8438

2,4-Difluorophenylboronic acid (contains varying amounts of anhydride)

CAS: 144025-03-6

Formula: C₆H₅BF₂O₂

Purity: 97%

Color and Shape: Solid, Chunks or Crystalline Powder or Flakes or Powder

Molecular weight: 157.91

Ref: 10-F011029

2,4-Difluorophenylboronic Acid extrapure, 95%

CAS: 144025-03-6

Formula: C₆H₅BF₂O₂

Purity: min. 95%

Color and Shape: White to off - white, Crystalline powder

Molecular weight: 157.9

Ref: SR-90309

2,4-Difluorophenylboronic Acid

Controlled Product

CAS: 144025-03-6

Applications 2,4-Difluorophenylboronic Acid is used as a reagent in suzuki-miyaura coupling reactions such as in the synthesis of enantiomerically pure 3,3'-bis-arylated BINOL derivatives. Also used in the synthesis of highly efficient phospherescent iridium (III) complexes which are used for light-emiiting diodes.
References Qu, B., et al.: J. Org. Chem., 81, 745 (2016); Tao, P., et al.: Adv. Funct. Mater., 26, 881 (2016);

Formula: C₆H₅BF₂O₂

Color and Shape: Neat

Molecular weight: 157.91

Ref: TR-D447295