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CAS 144073-15-4

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FMOC-D-ALA-CL

Description:
FMOC-D-ALA-CL, or 9-fluorenylmethoxycarbonyl-D-alanine chloride, is a derivative of the amino acid D-alanine, commonly used in peptide synthesis and as a protecting group in organic chemistry. The FMOC group is a widely utilized protecting group for amines due to its stability under various reaction conditions and ease of removal. This compound typically appears as a white to off-white solid and is soluble in organic solvents like dichloromethane and dimethylformamide. Its structure features a fluorenylmethoxycarbonyl moiety attached to the D-alanine backbone, with a chloride substituent that can participate in further reactions. FMOC-D-ALA-CL is particularly valuable in solid-phase peptide synthesis, where it helps to protect the amino group during the coupling of amino acids. The compound must be handled with care, as it can be sensitive to moisture and light, which may affect its stability. Proper storage in a cool, dry place is recommended to maintain its integrity for laboratory use.
Formula:C18H16ClNO3
Synonyms:
  • Fmoc-D-Alanyl Chloride
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